Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Gpc3 selectively suppresses subcutaneous adipogenesis in diet-induced obesity.
PMID 41779769 · PMC12978566 · PLoS biology · 2026 · 8 claims · 8 setups
Gpc3 is an obesity-responsive gene exhibiting reciprocal expression patterns between subcutaneous and visceral adipose depots in mice and humans
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Has reproduction · 71
IL-6 trans-Signaling Regulates Neutrophilic Inflammation in Alcohol-Associated Hepatitis.
PMID 40562277 · PMC13168973 · The American journal of pathology · 2026 · 8 claims · 8 setups
Hepatic IL-6R expression progressively declines with increasing severity of alcohol-related liver disease, from normal to early ASH to nonsevere and severe AH
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Has reproduction
Effects of Pharmacological Thermogenic Adipocyte Activation on Metabolism and Atherosclerotic Plaque Regression.
PMID 30813320 · PMC6412269 · Nutrients · 2019 · 8 claims · 7 setups
Chronic dietary CL316,243 treatment reduces adiposity and enhances body weight loss independent of food intake in LDLR-deficient mice
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Alternative polyadenylation mediated the downregulation of lysophosphatidylglycerol acyltransferase 1 in metabolic dysfunction-associated steatotic liver disease.
PMID 41507908 · PMC12879358 · Lipids in health and disease · 2026 · 8 claims · 8 setups
Early hepatocyte-specific APA remodeling, characterized by 3' UTR lengthening of metabolism-related genes (especially LPGAT1), occurs in MASLD and is established before fibrosis progression