Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Genome annotation errors in pathway databases due to semantic ambiguity in partial EC numbers.
PMID 16034025 · PMC1179732 · Nucleic acids research · 2005 · 7 claims · 4 setups
Partial EC numbers are semantically ambiguous, and databases that assign a gene to all reactions sharing the same partial EC number make a faulty inference, causing systematic misannotation.
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KEGG for linking genomes to life and the environment.
PMID 18077471 · PMC2238879 · Nucleic acids research · 2008 · 8 claims · 4 setups
KEGG provides a reference knowledge base for linking genomes to life via PATHWAY mapping and to the environment via BRITE mapping.
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From genomics to chemical genomics: new developments in KEGG.
PMID 16381885 · PMC1347464 · Nucleic acids research · 2006 · 8 claims · 5 setups
KEGG BRITE has been formally added as a fourth main KEGG database to establish a logical foundation for functional interpretation and pathway reconstruction.
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LMPD: LIPID MAPS proteome database.
PMID 16381922 · PMC1347484 · Nucleic acids research · 2006 · 8 claims · 5 setups
LMPD is an object-relational database of lipid-associated protein sequences and annotations, publicly available from the LIPID MAPS Consortium website.
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The Edinburgh human metabolic network reconstruction and its functional analysis.
PMID 17882155 · PMC2013923 · Molecular systems biology · 2007 · 8 claims · 7 setups
EHMN is a high-quality, manually curated human metabolic network combining genome-based and literature-based (EMP) reconstruction, containing nearly 3000 reactions and over 2000 metabolic genes.
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Has reproduction · 30
Minimal metabolic pathway structure is consistent with associated biomolecular interactions.
PMID 24987116 · PMC4299494 · Molecular systems biology · 2014 · 8 claims · 8 setups
MinSpan, a mixed-integer linear optimization algorithm, computes the shortest, linearly independent pathways (sparsest basis of the null space of the stoichiometric matrix S) for genome-scale metabolic networks, which convex approaches (extreme pathways, elementary flux modes) cannot do at genome scale.
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Has reproduction · 83
Multimodal data integration for biologically-relevant artificial intelligence to guide adjuvant chemotherapy in stage II colorectal cancer.
PMID 40472802 · PMC12171563 · EBioMedicine · 2025 · 6 claims · 7 setups
AI-derived radiological clustering identifies stage II CRC patients with significantly different survival benefit from adjuvant chemotherapy