Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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PAH-former: Transfer learning for efficient discovery of pulmonary arterial hypertension-associated genes.
PMID 41790620 · PMC12965534 · PloS one · 2026 · 7 claims · 7 setups
PAH-former, a Geneformer model fine-tuned on public PAH scRNA-seq data, can perform in silico perturbation to identify and rank candidate PAH disease-associated genes
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Flamenco plasticity tunes somatic piRNAs and rewires isoforms, with implications for heritable transposon spread.
PMID 42009568 · PMC13097621 · Life science alliance · 2026 · 8 claims · 8 setups
Springer drives host gene expression changes via promoter-proximal intronic insertions at an AT-rich motif, with its 5′ LTR initiating transcription that splices into downstream host exons to create hybrid isoforms without adding coding sequence
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Has reproduction · 87
RNA-Seq transcriptome profiling identifies CRISPLD2 as a glucocorticoid responsive gene that modulates cytokine function in airway smooth muscle cells.
PMID 24926665 · PMC4057123 · PloS one · 2014 · 8 claims · 8 setups
Dexamethasone treatment (1 µM, 18 h) of primary human ASM cells differentially regulates 316 genes, including both known and previously uninvestigated glucocorticoid-responsive genes.
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High mitochondrial DNA stability in B-cell chronic lymphocytic leukemia.
PMID 19924307 · PMC2775629 · PloS one · 2009 · 7 claims · 5 setups
mtDNA control-region instability is not the primary causal factor in B-CLL
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Enhancing KLF15 activity in cardiomyocytes: a novel approach to prevent pathological reprogramming and fibrosis via nuclease-deficient dCas9VPR.
PMID 41771837 · PMC12953643 · Signal transduction and targeted therapy · 2026 · 8 claims · 8 setups
KLF15 transcriptional activity shows the most significant change among TFs in pathological cardiomyocytes during progressive hypertrophic remodeling, reflecting less effective repression of disease-associated genes.
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A spatially coordinated keratinocyte-fibroblast circuit recruits MMP9(+) myeloid cells to drive type I interferon-driven inflammation in photosensitive autoimmunity.
PMID 42032302 · PMC13226071 · Nature immunology · 2026 · 8 claims · 8 setups
MMP9+CD14+ myeloid cells are critical mediators of photosensitivity, expanding in lesional skin, producing IFNβ, and colocalizing with cytotoxic CD4+ T cells at the dermal-epidermal junction