Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Has reproduction · 50
Implementing the reuse of public DIA proteomics datasets: from the PRIDE database to Expression Atlas.
PMID 35701420 · PMC9197839 · Scientific data · 2022 · 8 claims · 5 setups
An open, containerised, Nextflow-orchestrated reanalysis pipeline combining metadata annotation, SWATH-MS analysis, statistical analysis, and Expression Atlas integration was developed for public DIA data.
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KEGG spider: interpretation of genomics data in the context of the global gene metabolic network.
PMID 19094223 · PMC2646283 · Genome biology · 2008 · 8 claims · 8 setups
KEGG spider, using a global 'pathway-free' metabolic network framework, provides deeper insight into metabolism variations than existing enrichment-based methods.
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Has reproduction · 68
Octopus-toolkit: a workflow to automate mining of public epigenomic and transcriptomic next-generation sequencing data.
PMID 29420797 · PMC5961211 · Nucleic acids research · 2018 · 7 claims · 3 setups
Octopus-toolkit is a stand-alone application that automatically installs required tools and retrieves/processes public epigenomic and transcriptomic NGS data (ChIP-seq, ATAC-seq, DNase-seq, MeDIP-seq, MNase-seq, RNA-seq) from GEO in a single step.
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Has reproduction · 50
Dynamics and regulation of mitotic chromatin accessibility bookmarking at single-cell resolution.
PMID 36696508 · PMC9876548 · Science advances · 2023 · 7 claims · 8 setups
Chromatin accessibility continually decreases from mitotic entry until metaphase, then gradually increases as chromosomes segregate.
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Nucleosome deposition and DNA methylation at coding region boundaries.
PMID 19723310 · PMC2768978 · Genome biology · 2009 · 8 claims · 8 setups
Nucleosomes and DNA methylation form distinct peaks just downstream of the start codon and just upstream of the stop codon, marking both ends of protein coding units genome-wide.
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A modular analysis framework for blood genomics studies: application to systemic lupus erythematosus.
PMID 18631455 · PMC2727981 · Immunity · 2008 · 7 claims · 8 setups
Transcriptional modules constructed from coordinately expressed genes across 8 diseases form stable, biologically coherent functional units