Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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The promoter and the enhancer region of the KLK 3 (prostate specific antigen) gene is frequently mutated in breast tumours and in breast carcinoma cell lines.
PMID 10188912 · PMC2362704 · British journal of cancer · 1999 · 7 claims · 5 setups
No mutations were found in the protein-coding exons of the PSA gene in breast tumours or cell lines
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Has reproduction · 93
The evolution of sexual signaling is linked to odorant receptor tuning in perfume-collecting orchid bees.
PMID 31932598 · PMC6957680 · Nature communications · 2020 · 8 claims · 6 setups
E. dilemma and E. viridissima are reproductively isolated genetically distinct lineages despite low genome-wide differentiation.
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Novel point mutation in the extracellular domain of the granulocyte colony-stimulating factor (G-CSF) receptor in a case of severe congenital neutropenia hyporesponsive to G-CSF treatment.
PMID 10449521 · PMC2195597 · The Journal of experimental medicine · 1999 · 7 claims · 8 setups
A novel C→A point mutation at nucleotide 850 of GCSFR cDNA causes a Pro→His substitution at position 206 (P206H) in the proline-rich hinge of the CRH domain of the G-CSF receptor extracellular domain in an SCN patient hyporesponsive to G-CSF.
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Modeling substance abuse for applications in proteomics.
PMID 20058165 · PMC3272758 · Methods in molecular biology (Clifton, N.J.) · 2009 · 8 claims · 5 setups
The intravenous self-administration paradigm models the reinforcing effects of abused drugs and allows biochemical alterations to be correlated with drug reinforcement.
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Has reproduction
Endogenous Fatty Acid Synthesis Drives Brown Adipose Tissue Involution.
PMID 33440156 · PMC8240962 · Cell reports · 2021 · 8 claims · 8 setups
Endogenous fatty acid synthesis (DNL), regulated by ChREBP, is the central driver of BAT whitening/involution at thermoneutrality.