Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Transient tumor exposure induces persistent functional defects in memory CD8(+) T cells.
PMID 42023146 · PMC13098610 · iScience · 2026 · 8 claims · 8 setups
Memory CD8+ T cells generated after transient tumor rejection (Tum-CD8+) display a distinct, partially exhausted phenotype compared to virus-induced memory cells (Vir-CD8+)
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T cell-intrinsic VISTA expression promotes resistance to CTLA-4 blockade by restricting CD8+ T cell responses.
PMID 41837284 · PMC12987620 · The Journal of clinical investigation · 2026 · 8 claims · 8 setups
Loss of T cell-intrinsic VISTA enhances early priming and short-term expansion of CD8+ T cells but this initial advantage fails to confer durable tumor control