Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Has reproduction · 67
Bioavailable Nutrients (N and P) and Precipitation Patterns Drive Cyanobacterial Blooms in Missisquoi Bay, Lake Champlain.
PMID 34683418 · PMC8537112 · Microorganisms · 2021 · 8 claims · 8 setups
High concentrations of N and P were typically measured in April and May, before blooms occurred.
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piRNABank: a web resource on classified and clustered Piwi-interacting RNAs.
PMID 17881367 · PMC2238943 · Nucleic acids research · 2008 · 6 claims · 4 setups
piRNABank is a web-accessible database storing empirically known piRNA sequences and annotations for human, mouse and rat.
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The distribution of SNPs in human gene regulatory regions.
PMID 16209714 · PMC1260019 · BMC genomics · 2005 · 8 claims · 6 setups
SNPs occur with higher density closer to the transcriptional start site within gene promoter regions than in further upstream regions
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Subfunctionalization of duplicated genes as a transition state to neofunctionalization.
PMID 15831095 · PMC1112588 · BMC evolutionary biology · 2005 · 8 claims · 2 setups
Subfunctionalization plays an important role in duplicate gene retention but functions as a transition state leading to neofunctionalization rather than as a terminal fate.
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Reverse polarization in amino acid and nucleotide substitution patterns between human-mouse orthologs of two compositional extrema.
PMID 17895298 · PMC2533592 · DNA research : an international journal for rapid publication of reports on genes and genomes · 2007 · 8 claims · 7 setups
Nucleotide and amino acid substitution trends between human-mouse orthologs are highly asymmetric and polarized in opposite directions for high-GC versus low-GC gene groups.
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Estimation of relevant variables on high-dimensional biological patterns using iterated weighted kernel functions.
PMID 18509521 · PMC2396875 · PloS one · 2008 · 7 claims · 6 setups
wKIERA combines a weighted-kernel discriminant (kernel perceptron) with an iterative stochastic probability estimation-of-distribution algorithm to estimate a relevance distribution over variables
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Has reproduction · 92
Prognostic biomarker discovery in pancreatic cancer through hybrid ensemble feature selection and multi-omics data.
PMID 41957754 · PMC13188360 · BioData mining · 2026 · 7 claims · 3 setups
The hEFS framework integrates data subsampling with multiple prognostic models (embedded and wrapper-based), aggregates feature rankings via a voting-theory-inspired approach, and selects the optimal feature subset via Pareto front optimization, eliminating user-defined thresholds.
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Has reproduction · 66
Horizontal transmission enables flexible associations with locally adapted symbiont strains in deep-sea hydrothermal vent symbioses.
PMID 35349333 · PMC9168483 · Proceedings of the National Academy of Sciences of the United States of America · 2022 · 8 claims · 6 setups
Host populations of Alviniconcha and Ifremeria are not genetically differentiated across an ~800-km geographic gradient
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Annotation and analysis of 10,000 expressed sequence tags from developing mouse eye and adult retina.
PMID 14519200 · PMC328454 · Genome biology · 2003 · 8 claims · 5 setups
Annotation of 8,633 high-quality non-mitochondrial/non-ribosomal ESTs shows 57% represent known genes and 43% are unknown or novel, with M15E having the highest proportion of novel ESTs
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Genome wide survey of G protein-coupled receptors in Tetraodon nigroviridis.
PMID 16022726 · PMC1187884 · BMC evolutionary biology · 2005 · 8 claims · 8 setups
466 Tetraodon GPCRs (Tnig-GPCRs) were identified genome-wide, of which 457 had not been previously reported
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ARED 3.0: the large and diverse AU-rich transcriptome.
PMID 16381826 · PMC1347415 · Nucleic acids research · 2006 · 7 claims · 6 setups
ARED 3.0 computationally mapped more than 4000 ARE-mRNAs to the human genome, representing 5-8% of human genes.
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Has reproduction · 67
A consensus approach to vertebrate de novo transcriptome assembly from RNA-seq data: assembly of the duck (Anas platyrhynchos) transcriptome.
PMID 25009556 · PMC4070175 · Frontiers in genetics · 2014 · 8 claims · 8 setups
Multiple k-mer (MK) assemblies are more complete than single k-mer (SK) assemblies, showing higher reads-mapped-back-to-transcripts (RMBT) and higher CEGMA complete-gene percentages for all three tools.