Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Has reproduction · 71
Protein structure quality assessment based on the distance profiles of consecutive backbone Cα atoms.
PMID 24555103 · PMC3892923 · F1000Research · 2013 · 8 claims · 8 setups
The distance between consecutive backbone Cα atoms in high-quality structures is normally distributed with mean 3.8 Å and standard deviation 0.04 Å, justifying a reference state in which all consecutive Cα atoms are 3.8 Å apart.
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Species-specific protein sequence and fold optimizations.
PMID 12487631 · PMC139977 · BMC bioinformatics · 2002 · 7 claims · 7 setups
Environmental niche is a significant factor explaining variability in amino acid composition across 100 complete genomes
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Natural selection of protein structural and functional properties: a single nucleotide polymorphism perspective.
PMID 18397526 · PMC2643940 · Genome biology · 2008 · 8 claims · 8 setups
The SNP A/S ratio is a robust measure of selective constraint, correlating with interspecies Ka/Ks ratios and with protein sequence conservation.