Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• Getting it right: being smarter about clinical trials.

  PMID 16608383 · PMC1435786 · PLoS medicine · 2006 · 9 claims · 8 setups

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  Bias and confounding in observational studies can produce misleading associations that are overturned by randomized trials (e.g., HRT).

  postmenopausal general patients men randomized population-based large

• Pharmacogenomics of gemcitabine: can genetic studies lead to tailor-made therapy?

  PMID 17595663 · PMC2360307 · British journal of cancer · 2007 · 8 claims · 14 setups

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  A SNP in the cytidine deaminase (CDA) gene (208G>A, haplotype *3) decreases gemcitabine clearance, increases Cmax/AUC, and increases neutropenia risk when gemcitabine is combined with platinum drugs or 5-FU

  japanese paraffin-embedded tumour recombinant prospective immunohistochemistry pcr

• Kinetoplastid genomics: the thin end of the wedge.

  PMID 18675383 · PMC2676795 · Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2008 · 8 claims · 8 setups

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  Completion of the T. brucei, T. cruzi, and L. major genome sequencing projects enabled numerous studies that would otherwise have been difficult or impossible.

  brucei major cruzi kinetoplastid whole-genome gene shotgun

• Multilocus sequence typing supports the hypothesis that Ochrobactrum anthropi displays a human-associated subpopulation.

  PMID 20021660 · PMC2810298 · BMC microbiology · 2009 · 8 claims · 6 setups

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  A novel Multi-Locus Sequence Typing (MLST) scheme for O. anthropi was developed for the first time, based on 7 genes (3490 nucleotides) evolving mostly by neutral mutations

  anthropi same candidate multi-locus pulsed-field antibiotyping

• Ecotype diversity and conversion in Photobacterium profundum strains.

  PMID 24824441 · PMC4019646 · PloS one · 2014 · 8 claims · 8 setups

  Has reproduction · 77

  No single gene restricts the environmental niche of each bathytype; instead a set of strain-specific genetic features confers depth-specific stress tolerance (temperature, pressure, nutrients).

  photobacterium profundum predicted orthologous whole-genome pulsed-field comparative

• Transcriptional readthrough precedes alternative splicing programs triggered in CML cells by imatinib.

  PMID 41860998 · PMC13004010 · Science advances · 2026 · 8 claims · 6 setups

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  Imatinib treatment induces transcriptional readthrough in K562 CML cells within 1 hour, before detectable gene expression or alternative splicing changes

  k562 imatinib-resistant long-read short-read rt-qpcr

• LIMCH1-enriched extracellular vesicles promote vascular permeability in early-onset preeclampsia.

  PMID 41604492 · PMC12851021 · Science advances · 2026 · 8 claims · 8 setups

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  LIMCH1 is identified as an Eo-PE-associated EV protein via serum sEV proteomics combined with GEO placental transcriptome datasets

  serum placenta jar huvecs lc-ms exoview nanoflow

• Splicing variants in MYRF cause partial loss of function in the retinal pigment epithelium leading to nanophthalmos.

  PMID 41746734 · PMC13043084 · JCI insight · 2026 · 8 claims · 8 setups

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  The dG-MYRF C-terminal frameshift variant undergoes normal homotrimerization, cleavage, and nuclear localization but shows reduced steady-state levels of the C-terminal cleavage product and decreased transcriptional activation of target genes.

  arpe-19 myrf rpe e17.5 immunofluorescence computational cycloheximide

• Homeodomain protein Sxi1α independently controls cell-cell fusion and gene expression during sexual reproduction in Cryptococcus deneoformans.

  PMID 41818280 · PMC13001979 · PLoS genetics · 2026 · 8 claims · 8 setups

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  Sxi1α has a previously unrecognized inhibitory role in same-sex (α-α) cell-cell fusion during unisexual reproduction

  sxi1α cerevisiae deneoformans sxi1αδ alphafold3 yeast crispr

• Taxonomic and Functional Assessment of Microbial Communities in Urban Runoff-Contaminated Mangrove Sediments.

  PMID 41991668 · PMC13086700 · Current microbiology · 2026 · 7 claims · 7 setups

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  Colhereiro mangrove shows more pronounced signatures of chronic urban pollution than Araçá Bay, including elevated macronutrients and enrichment of sulfur-metabolizing bacteria and Arcobacter

  mangrove pooled bacterial selected 16s sediment bacterial