Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• Temporal multiomics gene expression data across human embryonic stem cell-derived polyhormonal cell differentiation.

  PMID 41545424 · PMC12920657 · Scientific data · 2026 · 8 claims · 8 setups

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  Generated a high-resolution, time-resolved multi-omics dataset (RNA-seq, ribosome profiling, and quantitative proteomics) tracking mRNA, translation, and protein dynamics across hESC differentiation into definitive endoderm and polyhormonal pancreatic cells

  hesc-derived rues2 extracted star-aligned rna-seq ribosome quantitative

• Identification of RNA-Binding Protein Targets with HyperTRIBE in Saccharomyces cerevisiae.

  PMID 37240377 · PMC10218906 · International journal of molecular sciences · 2023 · 7 claims · 8 setups

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  HyperTRIBE was successfully established in S. cerevisiae by fusing an RBP to the hyper-active catalytic domain of human ADAR2 (E488Q), marking target transcripts with A-to-G editing events detectable by high-throughput sequencing

  cerevisiae khd1 wild-type bfr1-heterozygous hypertribe western meme

• The exonuclease Xrn1 activates transcription and translation of mRNAs encoding membrane proteins.

  PMID 30899024 · PMC6428865 · Nature communications · 2019 · 8 claims · 8 setups

  Has reproduction · 85

  Xrn1 promotes translation of a specific group of transcripts encoding membrane proteins

  cerevisiae western renilla polysome

• Single-cell and isoform-specific translational profiling of the mouse brain.

  PMID 41708856 · PMC13102718 · Nature · 2026 · 8 claims · 8 setups

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  Ribo-STAMP coupled with short-read and long-read single-cell RNA-seq enables isoform-sensitive single-cell translatome profiling in the brain

  cortical curated hippocampus bulk immunocytochemistry eclip