Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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A machine learning approach uncovers principles and determinants of eukaryotic ribosome pausing.
PMID 39423268 · PMC11488575 · Science advances · 2024 · 8 claims · 5 setups
An unsupervised ML pipeline using the extended isolation forest (EIF) algorithm can reliably detect ribosome pausing sites from noisy, coverage-biased RiboSeq data across expression levels
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Has reproduction · 76
Estimation of peptide elongation times from ribosome profiling spectra.
PMID 33885812 · PMC8136808 · Nucleic acids research · 2021 · 7 claims · 4 setups
A maximum likelihood statistical model using 915 context-defining parameters can neutralize technical biases (e.g. RNase cleavage preferences) in Ribo-Seq data and estimate peptide elongation times at single-codon resolution.