Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• In silico screening of mutational effects on enzyme-proteic inhibitor affinity: a docking-based approach.

  PMID 17559675 · PMC1913526 · BMC structural biology · 2007 · 8 claims · 4 setups

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  A rigid-body docking-based approach can predict mutational effects on binding energetics for three structurally distinct enzyme-proteic inhibitor systems (hRI-Ang, Bn-Bs, BPTI-β-Trypsin)

  ribonuclease barnase bovine hri-ang rigid-body cluster

• Interaction profile-based protein classification of death domain.

  PMID 15189571 · PMC459208 · BMC bioinformatics · 2004 · 7 claims · 6 setups

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  An SVM-based classifier using Residue Pair Interaction Profiles (RPIPs) can classify death domain superfamily members into subfamilies with 89% average cross-validation accuracy

  homology-modeled death homology putative rigid-body homology model

• Evaluating native-like structures of RNA-protein complexes through the deep learning method.

  PMID 36828844 · PMC9958188 · Nature communications · 2023 · 8 claims · 7 setups

  Has reproduction · 67

  DRPScore identifies native-like RNA-protein structures with higher success rates than ITScore-PR, DARS-RNP, and 3dRPC across bound and unbound testing sets.

  bound-bound unbound-bound unbound-unbound bacillus structure interface secondary