Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

Publications 1.3k Datasets 392.5k Experiments 981

Assay: rna-seq ✕ Clear

Functional analysis of target of rapamycin in regulating mycelial growth and development in Penicillium italicum.

PMID 41724910 · PMC12979286 · International microbiology : the official journal of the Spanish Society for Microbiology · 2026 · 6 claims · 7 setups

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P. italicum possesses a single TOR gene (PiTOR, PITC_004820) encoding a 2,384 amino acid protein with conserved domain architecture

italicum blast colony light
Multi-cohort and single-cell profiling of aging genes reveals prognostic and therapeutic targets in breast cancer.

PMID 41732271 · PMC12924738 · iScience · 2026 · 8 claims · 7 setups

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The eight-gene MLAG signature outperforms 100 previously published prognostic models across 12 independent breast cancer cohorts

tcga-brca senescent normal single-cell machine univariate gene
Cardiac conduction system malformations in heterotaxy result from dysregulated Pitx2 expression.

PMID 41734036 · PMC13043103 · JCI insight · 2026 · 8 claims · 8 setups

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Cryptic-/- embryos (right isomerism model) develop bilateral sinoatrial nodes and an ectopic anterior AV node and bundle, accompanied by reduced Pitx2 expression

cryptic embryo pitx2 lefty1 situ immunostaining cardiac
Rare variant analyses provide insights into the genetic architecture of endometriosis.

PMID 41736152 · PMC13001359 · Human genomics · 2026 · 7 claims · 8 setups

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Gene-based burden testing of rare LoF and deleterious missense variants identifies SOGA1 as significantly associated with endometriosis after Bonferroni correction

unrelated finngen biobank soga1 exome gene-based protein-protein
Benchmarking LLM-based agents for single-cell omics analysis.

PMID 41742311 · PMC13064268 · Genome biology · 2026 · 8 claims · 8 setups

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Introduces a comprehensive benchmarking evaluation system comprising an open-source agent platform, 18 evaluation metrics across four dimensions, and 50 real-world single-cell omics tasks

agent single-cell spatial scatac-seq llm-agent scrna-seq spatial
Splicing variants in MYRF cause partial loss of function in the retinal pigment epithelium leading to nanophthalmos.

PMID 41746734 · PMC13043084 · JCI insight · 2026 · 8 claims · 8 setups

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The dG-MYRF C-terminal frameshift variant undergoes normal homotrimerization, cleavage, and nuclear localization but shows reduced steady-state levels of the C-terminal cleavage product and decreased transcriptional activation of target genes.

arpe-19 myrf rpe e17.5 immunofluorescence computational cycloheximide
Centromere organization and epigenetic regulation in Aristolochia fimbriata.

PMID 41761339 · PMC13049873 · Genome biology · 2026 · 8 claims · 8 setups

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A complete gapless telomere-to-telomere (T2T) genome assembly of A. fimbriata was constructed, substantially improving on the previous v1 assembly.

aristolochia fimbriata pacbio hi-c cenh3
Colonic Engyodontium fungus triggers neutrophil antimicrobial activity to suppress Lactobacillus johnsonii-derived glutamic acid-maintained Tregs.

PMID 41770903 · PMC13078882 · The Journal of clinical investigation · 2026 · 8 claims · 8 setups

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A commensal Ascomycota fungus, Engyodontium sp., was isolated live from mouse feces using a Dectin-2-Fc fusion protein

feces colonic colon ncm460 its flow qpcr
Estropausal gut microbiota transplant improves measures of ovarian function in adult mice.

PMID 41776310 · PMC13004687 · Nature aging · 2026 · 8 claims · 7 setups

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Young and estropausal female mice have distinct, separable gut microbial profiles (beta and alpha diversity) across multiple cohorts.

fecal young gut vcd-induced 16s ovarian picrust2
A hormetic transcriptional program coregulates invasion, proliferation and dormancy to define metastatic potential.

PMID 41781391 · PMC13077004 · Nature communications · 2026 · 8 claims · 7 setups

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Prrx1 is a master regulator of dissemination that, beyond promoting invasion, represses proliferation (via Ccnd1/2, Cdkn2a/b/c) and activates a dormancy program (Gas6, Mme, Ogn)

infiltrating metabric facs-sorted pymt immunohistochemistry bioinformatic rt-qpcr
Differential fates of Kazald gene quartet: Ancestral roles in skeletogenesis and regeneration to putative innovations in fish and birds.

PMID 41782814 · PMC12955574 · iScience · 2026 · 8 claims · 8 setups

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The regeneration-associated axolotl gene is Kazald2, not Kazald1

axolotl jawed kazald cyclostome reciprocal tblastn maximum
Matcha alleviates sneezing response in a murine model of allergic rhinitis.

PMID 41786771 · PMC13022397 · NPJ science of food · 2026 · 8 claims · 8 setups

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Matcha suppresses allergen-induced immediate nasal response (INR) and nasal hyperresponsiveness (NHR) in an OVA-immunized mouse model

balb fecal cd4+ expanded sneeze nasal serum
NDUFA4L2 regulates the progression and chemotherapy sensitivity of HNSCC by inhibiting PANoptosis.

PMID 41787028 · PMC13087130 · NPJ precision oncology · 2026 · 8 claims · 8 setups

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Elevated NDUFA4L2 expression is associated with poor survival and chemotherapy resistance in HNSCC

carcinoma hnscc cal27 oscc non-negative kaplan-meier western
PVT1 lincRNA signals an androgen-dependent transcriptional activation program of oncogenes in prostate cancer cells.

PMID 41792045 · PMC13139993 · International journal of cancer · 2026 · 8 claims · 7 setups

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PVT1 knockdown significantly reduces LNCaP cell proliferation and increases sensitivity to apoptosis

lncap tcga-prad rt-qpcr trypan transwell
ADAR1 regulates dsRNA formation in nuclear and mitochondrial transcripts through editing-dependent and -independent mechanisms.

PMID 41800619 · PMC13171160 · Cell reports · 2026 · 8 claims · 8 setups

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Human ADAR1 downregulates self-dsRNA abundance through both editing-dependent and editing-independent mechanisms

hek-293t adar1 dermal e912a antibody western nuclease
Reliable Inference of Phylogenomic Relationship via Assembly-Based Strategy Accommodating Raw Reads and Proteins.

PMID 41800729 · PMC12969758 · Molecular ecology resources · 2026 · 7 claims · 8 setups

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VEHoP infers protein-coding regions from diverse input types (raw reads, draft genomes, transcriptomes, annotated genomes) and automates generation of orthologous alignments, concatenated supermatrices, and phylogenetic trees in a single pipeline run.

ostreida crassostrea catfish insects phylogenomic sequencing reduced
Genome evolution and regulatory dynamics underlying salt stress tolerance in the halophyte Halogeton arachnoideus.

PMID 41803406 · PMC13103082 · Communications biology · 2026 · 8 claims · 8 setups

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A high-quality, chromosome-scale genome assembly of H. arachnoideus was generated using PacBio HiFi and Hi-C sequencing.

arachnoideus pacbio high-throughput illumina
miR-203 facilitates timely cell fate transitions via epigenetic modulation during early embryogenesis.

PMID 41811946 · PMC12978216 · Science advances · 2026 · 8 claims · 8 setups

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miR-203 is required for a timely totipotency-to-pluripotency transition during early mouse embryogenesis

preimplantation 8-cell mice mir-203 qrt-pcr genotyping time-lapse
Genetic evidence supporting obesity as a risk factor for lung squamous cell carcinoma and the identification of MFAP1 as a shared genetic target.

PMID 41820721 · PMC13096280 · Discover oncology · 2026 · 8 claims · 8 setups

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BMI and LUSC show a significant positive genome-wide genetic correlation, robust to constrained-intercept sensitivity analysis and replicated by GNOVA.

gwas gtex scrna-seq ldsc gnova ρ-hess
DLX2 marks an immunosuppressive dendritic-cell program that reshapes cytotoxic immunity and marks a tolerogenic microenvironment in lung adenocarcinoma.

PMID 41761000 · PMC13043845 · Discover oncology · 2026 · 8 claims · 8 setups

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Neuroactive ligand–receptor signaling is among the most significantly upregulated pathways in LUAD relative to normal lung tissue.

tcga-luad tcga luad dendritic-cell bulk survival pan-cancer

Experiments

Functional analysis of target of rapamycin in regulating mycelial growth and development in Penicillium italicum.

Multi-cohort and single-cell profiling of aging genes reveals prognostic and therapeutic targets in breast cancer.

Cardiac conduction system malformations in heterotaxy result from dysregulated Pitx2 expression.

Rare variant analyses provide insights into the genetic architecture of endometriosis.

Benchmarking LLM-based agents for single-cell omics analysis.

Splicing variants in MYRF cause partial loss of function in the retinal pigment epithelium leading to nanophthalmos.

Centromere organization and epigenetic regulation in Aristolochia fimbriata.

Colonic Engyodontium fungus triggers neutrophil antimicrobial activity to suppress Lactobacillus johnsonii-derived glutamic acid-maintained Tregs.

Estropausal gut microbiota transplant improves measures of ovarian function in adult mice.

A hormetic transcriptional program coregulates invasion, proliferation and dormancy to define metastatic potential.

Differential fates of Kazald gene quartet: Ancestral roles in skeletogenesis and regeneration to putative innovations in fish and birds.

Matcha alleviates sneezing response in a murine model of allergic rhinitis.

NDUFA4L2 regulates the progression and chemotherapy sensitivity of HNSCC by inhibiting PANoptosis.

PVT1 lincRNA signals an androgen-dependent transcriptional activation program of oncogenes in prostate cancer cells.

ADAR1 regulates dsRNA formation in nuclear and mitochondrial transcripts through editing-dependent and -independent mechanisms.

Reliable Inference of Phylogenomic Relationship via Assembly-Based Strategy Accommodating Raw Reads and Proteins.

Genome evolution and regulatory dynamics underlying salt stress tolerance in the halophyte Halogeton arachnoideus.

miR-203 facilitates timely cell fate transitions via epigenetic modulation during early embryogenesis.

Genetic evidence supporting obesity as a risk factor for lung squamous cell carcinoma and the identification of MFAP1 as a shared genetic target.

DLX2 marks an immunosuppressive dendritic-cell program that reshapes cytotoxic immunity and marks a tolerogenic microenvironment in lung adenocarcinoma.