Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Has reproduction · 67
NET-prism enables RNA polymerase-dedicated transcriptional interrogation at nucleotide resolution.
PMID 31156037 · PMC6693550 · RNA biology · 2019 · 8 claims · 7 setups
NET-prism, an adapted NET-seq protocol using immunoprecipitation of Pol II-associated factors, enables strand-specific, nucleotide-resolution interrogation of transcription dynamics for any Pol II-interacting protein.
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Developmental convergence and divergence in human stem cell models of autism.
PMID 41611887 · PMC12999519 · Nature · 2026 · 8 claims · 8 setups
Different ASD-associated mutations show the largest mutation-specific transcriptional changes early in hCO differentiation but converge on shared transcriptional changes as development progresses
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Molecular interactome of HNRNPU reveals regulatory networks in neuronal differentiation and DNA methylation.
PMID 41674383 · PMC12895067 · Nucleic acids research · 2026 · 7 claims · 8 setups
HNRNPU forms extensive protein networks including an association with the mammalian SWI/SNF chromatin-remodeling complex
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Bromodomain protein IBD1 bridges histone acetylation and H2A.Z deposition to fine-tune transcription.
PMID 41728948 · PMC12926916 · Nucleic acids research · 2026 · 8 claims · 8 setups
IBD1's bromodomain recognizes H3K9/K14 di-acetylation to recruit the SWR complex subunit ARP6, ensuring precise H2A.Z incorporation into chromatin