Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Single-cell transcriptomics of human embryos identifies multiple sympathoblast lineages with potential implications for neuroblastoma origin.
PMID 33833454 · PMC7610777 · Nature genetics · 2021 · 8 claims · 8 setups
In human embryos, intra-adrenal sympathoblasts are directly derived from nerve-associated Schwann cell precursors (SCPs), similarly to chromaffin cells
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HIF sustain a transcriptional regulatory circuit of EPAS1 expression in renal clear cell carcinoma.
PMID 41714613 · PMC12921326 · Nature communications · 2026 · 8 claims · 8 setups
HIF-2α mRNA is specifically overexpressed in ccRCC tumor tissue/cells compared to normal kidney, while it is reduced in papillary and chromophobe RCC
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Heterozygous ADAR mutant mice exhibit RNA sensing-dependent neuroinflammation and phenotypes associated with Aicardi-Goutières syndrome.
PMID 41704749 · PMC12907846 · iScience · 2026 · 8 claims · 8 setups
A heterozygous Adar G1007R (mouse G956R/G567) mouse model recapitulates the genetic and inflammatory features of human ADAR G1007R AGS patients
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Splicing variants in MYRF cause partial loss of function in the retinal pigment epithelium leading to nanophthalmos.
PMID 41746734 · PMC13043084 · JCI insight · 2026 · 8 claims · 8 setups
The dG-MYRF C-terminal frameshift variant undergoes normal homotrimerization, cleavage, and nuclear localization but shows reduced steady-state levels of the C-terminal cleavage product and decreased transcriptional activation of target genes.