Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• Characterization of Phytoene Desaturase Knockout Carotenoid-Deficient Microalgal Mutants Generated by Cas9-Ribonucleoprotein Complexes.

  PMID 41757451 · PMC12947057 · Physiologia plantarum · 2026 · 8 claims · 8 setups

  Full-text index only

  Cas9-ribonucleoprotein (RNP) complexes with dual sgRNAs targeting PDS exon 1 and a donor DNA sequence successfully generated multiple white PDS-knockout Chlamydomonas transformants

  pcr-amplified chlamydomonas transformant methanol rnp electroporation-based pcr

• Integrative miRNA-mRNA Network and Molecular Dynamics-Based Identification of Therapeutic Candidates for Paroxysmal Nocturnal Hemoglobinuria.

  PMID 41599741 · PMC12845513 · Pharmaceuticals (Basel, Switzerland) · 2026 · 8 claims · 8 setups

  Full-text index only

  A PIGA-knockout (PIGA-KO) THP-1 cell model was successfully established using CRISPR/Cas9 RNP technology as a PNH model

  thp-1 literature-validated pnh cxcl8 crispr rt-qpcr bulk

• Molecular interactome of HNRNPU reveals regulatory networks in neuronal differentiation and DNA methylation.

  PMID 41674383 · PMC12895067 · Nucleic acids research · 2026 · 7 claims · 8 setups

  Full-text index only

  HNRNPU forms extensive protein networks including an association with the mammalian SWI/SNF chromatin-remodeling complex

  ipsc-derived computational neocortical ip-ms formaldehyde alphapulldown expression-weighted

• Splicing bioinformatics to biology.

  PMID 16732900 · PMC1779529 · Genome biology · 2006 · 8 claims · 8 setups

  Full-text index only

  Mutually exclusive selection of Dscam exon 6 variants is governed by base pairing between a conserved intronic docking site and selector sequences adjacent to each alternative exon.

  dscam alternative heterologous expressing comparative dicodon reporter

• Omics-aided design genome editing strategy for challenging human immortalized cell models.

  PMID 41678468 · PMC12900285 · PloS one · 2026 · 6 claims · 4 setups

  Full-text index only

  Omics profiling identifies bottlenecks associated with poor precise KI efficiency in hard-to-engineer cells

  mcf7 deep-targeted bulk dia-based

• Features affecting Cas9-induced editing efficiency and patterns in tomato: evidence from a large CRISPR dataset.

  PMID 41877594 · PMC13014117 · The Plant journal : for cell and molecular biology · 2026 · 8 claims · 5 setups

  Full-text index only

  Chromatin accessibility significantly increases editing efficiency, with higher editing at targets in accessible versus inaccessible chromatin.

  tomato analysis using pcr mars-seq atac-seq