Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• In vivo structural characterization of the SARS-CoV-2 RNA genome identifies host proteins vulnerable to repurposed drugs.

  PMID 33636127 · PMC7871767 · Cell · 2021 · 8 claims · 8 setups

  Has reproduction · 95

  icSHAPE was used to determine the in vivo and in vitro structural landscape of the SARS-CoV-2 RNA genome in infected Huh7.5.1 cells, plus UTR structures of six other coronaviruses

  huh7.5.1 sars-cov-2 utrs 18s icshape structure deep-learning

• A computationally-enhanced hiCLIP atlas reveals Staufen1-RNA binding features and links 3' UTR structure to RNA metabolism.

  PMID 37013995 · PMC10164587 · Nucleic acids research · 2023 · 7 claims · 5 setups

  Has reproduction · 72

  Extending computational analysis of hiCLIP data (recovering truncated-linker hybrids, direct proximity ligation hybrids without a linker, and short-loop non-hybrid duplexes) increases identified STAU1 duplexes ~10-fold over the original analysis

  hek293t hela hiclip paris ric-seq