Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• Loss of Ezh2 promotes M2-like macrophage polarization in hepatocellular carcinoma.

  PMID 41869562 · PMC12999353 · iScience · 2026 · 8 claims · 7 setups

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  Hepa1-6 conditioned media (CM) induces M2-like polarization of BMDMs in a dose-dependent manner

  bmdms rt-qpcr western flow

• Microglia cause HIV-induced transcriptional and metabolic changes in human neural organoids.

  PMID 41857366 · PMC13021996 · Communications biology · 2026 · 8 claims · 7 setups

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  Microglia are essential for driving HIV-induced transcriptional changes and neuroinflammation in neural organoids

  hipsc-derived neural mno supernatant flow elisa immunocytochemistry

• Irisin ameliorates obesity and insulin resistance via adipose tissue IL-33 and regulatory T cells.

  PMID 41933175 · PMC13052164 · Nature metabolism · 2026 · 8 claims · 8 setups

  Has reproduction · 48

  Irisin modulates adipose tissue inflammation by increasing IL-33 production and preserving ST2+ regulatory T cells in white adipose tissues, thereby improving obesity and glucose intolerance.

  4-week-old hfd-fed bat iwat aav8-mediated body intraperitoneal

• Aging-dependent microglial heterogeneity worsens outcomes in models of traumatic brain injury.

  PMID 41926211 · PMC13262727 · The Journal of clinical investigation · 2026 · 8 claims · 8 setups

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  Aged TBI brains predominantly harbor proinflammatory NLRP3+ microglia, whereas young TBI brains harbor neuroprotective Lysozyme+ microglia

  injured sorted facs-purified cas9-gfp scrna-seq atac-seq untargeted

• Heterogeneity and Differentiation Trajectories of Infiltrating CD8+ T Cells in Lung Adenocarcinoma.

  PMID 36358600 · PMC9658355 · Cancers · 2022 · 7 claims · 8 setups

  Has reproduction · 67

  Infiltrating CD8+ T cells in LUAD can be divided into ten transcriptionally distinct subsets: eight cytotoxic (CTL) subsets, one naive-like (NTL) subset, and one exhausted (ETL) subset.

  luad tcga cd8+ degs single-cell cibersort survival