Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• Integrating single-cell and single-nucleus datasets improves bulk RNA-seq deconvolution.

  PMID 41895263 · PMC13106970 · Cell reports methods · 2026 · 8 claims · 5 setups

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  scRNA-seq references yield significantly higher Pearson correlation and lower RMSE than snRNA-seq references for deconvolution across all four tissue datasets

  adipose same fat-cell real pseudobulk single-cell synthetic

• CD14(lo)CD301b(+) macrophages gathering as a proangiogenic marker in adipose tissues.

  PMID 39645040 · PMC11745947 · Journal of lipid research · 2025 · 8 claims · 8 setups

  Has reproduction · 59

  Cd14−/− mice exhibit a leaner body shape and are protected from HFD-induced obesity compared to WT mice

  epididymal adipose cd14low macrophage bulk scrna-seq pseudotime

• Gpc3 selectively suppresses subcutaneous adipogenesis in diet-induced obesity.

  PMID 41779769 · PMC12978566 · PLoS biology · 2026 · 8 claims · 8 setups

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  Gpc3 is an obesity-responsive gene exhibiting reciprocal expression patterns between subcutaneous and visceral adipose depots in mice and humans

  paired iwat asat subcutaneous dia single-cell qpcr

• Functional module detection through integration of single-cell RNA sequencing data with protein-protein interaction networks.

  PMID 33138772 · PMC7607865 · BMC genomics · 2020 · 8 claims · 6 setups

  Has reproduction · 83

  scPPIN integrates scRNA-seq-derived p-values with PPINs to detect maximum-weight connected subgraphs (active/functional modules) via an exact Steiner-tree approach

  liver hepatocyte detected adipose single-cell differential protein-protein

• Expression Atlas in 2026: enabling FAIR and open expression data through community collaboration and integration.

  PMID 41370097 · PMC12807774 · Nucleic acids research · 2026 · 8 claims · 8 setups

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  Expression Atlas has expanded to >4500 studies from 67 species, with increased proteomics coverage and updated GTEx tissue profiles

  species pig tissues gtex microarray bulk ms-based