Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Bidirectional CRISPR screens decode a GLIS3-dependent fibrotic cell circuit.
PMID 41501466 · PMC12820784 · Nature · 2026 · 8 claims · 8 setups
Inflammation-associated fibroblasts (IAFs), induced by proinflammatory FCN1+IL1B+ macrophages, produce profibrotic IL-11 and drive fibrosis in IBD
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Dictionary of human intestinal organoid responses to secreted niche factors at single cell resolution.
PMID 41513700 · PMC12891662 · Nature communications · 2026 · 8 claims · 8 setups
Cytomix (TNFɑ+IFNɣ+IL1β) treatment of human colon organoids best recapitulates molecular features of human IBD compared to DSS or irradiation injury models.
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Multi-omics reveal vitamin D regulation of immune-gut microbiome interactions and tolerogenic pathways in inflammatory bowel disease.
PMID 41895287 · PMC13130636 · Cell reports. Medicine · 2026 · 8 claims · 7 setups
12 weeks of vitamin D treatment decreases disease activity scores and inflammatory markers (fecal calprotectin) and improves quality of life in IBD patients
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A tumor-intrinsic WNT-inhibitory NOTUM program drives immune resistance in microsatellite stable colorectal cancer.
PMID 42097145 · PMC13198260 · Cell reports. Medicine · 2026 · 8 claims · 7 setups
A distinct NOTUM/NKD1/APCDD1-high, WNT-inhibitory cancer cell population (WICC) emerges predominantly in advanced-stage MSS CRC