Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

Publications 1.3k Datasets 392.5k Experiments 5

System / cell line: ileum ✕ Assay: scrna ✕ Clear

Tachykinin signaling defines distinct populations of glia in the enteric nervous system.

PMID 41512855 · PMC12832054 · Neuron · 2026 · 8 claims · 8 setups

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Mucosal and muscularis glia are transcriptionally distinct populations, with mucosal glia resembling microglia and muscularis glia resembling satellite glia/astrocytes

ileum gfp+ intestinal intestine bulk scrna-seq bayesprism
Paneth cell SIRT1 deficiency increases intestinal stress resistance by modulating the gut microbiota.

PMID 41826553 · PMC13076647 · EMBO reports · 2026 · 8 claims · 8 setups

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Generated a novel Paneth-cell-specific SIRT1 knockout mouse model (SIRT1 PKO, Sirt1 f/f;Defa6-Cre+)

small immune facs-sorted ileum single-cell facs qpcr
Enteroendocrine cell lineages that differentially control feeding and gut motility.

PMID 36810133 · PMC10032656 · eLife · 2023 · 6 claims · 8 setups

Has reproduction · 88

Vil1-p2a-FlpO knock-in mice combined with lineage-specific Cre lines enable highly selective intersectional genetic access to major enteroendocrine cell lineages (serotonin/enterochromaffin, GLP1, CCK, somatostatin, GIP) in vivo

neurod1-cre neurog3-cre intestinal vil1-p2a-flpo single-cell fluorescence-activated two-color
Genetic evidence supporting obesity as a risk factor for lung squamous cell carcinoma and the identification of MFAP1 as a shared genetic target.

PMID 41820721 · PMC13096280 · Discover oncology · 2026 · 8 claims · 8 setups

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BMI and LUSC show a significant positive genome-wide genetic correlation, robust to constrained-intercept sensitivity analysis and replicated by GNOVA.

gwas gtex scrna-seq ldsc gnova ρ-hess
Dietary conjugated linoleic acid enhances resistance to Salmonella infection by promoting PPARγ-mediated metabolic reprogramming and effector function in CD8⁺ T cells.

PMID 41964110 · PMC13078244 · Gut microbes · 2026 · 8 claims · 12 setups

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Dietary CLA supplementation enhances host resistance to Salmonella Typhimurium infection

ileal mice serum culture 16s untargeted bulk

Experiments

Tachykinin signaling defines distinct populations of glia in the enteric nervous system.

Paneth cell SIRT1 deficiency increases intestinal stress resistance by modulating the gut microbiota.

Enteroendocrine cell lineages that differentially control feeding and gut motility.

Genetic evidence supporting obesity as a risk factor for lung squamous cell carcinoma and the identification of MFAP1 as a shared genetic target.

Dietary conjugated linoleic acid enhances resistance to Salmonella infection by promoting PPARγ-mediated metabolic reprogramming and effector function in CD8⁺ T cells.