Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Aurkb deficiency disrupts microglial development, homeostasis and hinders remyelination following cuprizone-induced demyelination.
PMID 41704758 · PMC12907124 · iScience · 2026 · 8 claims · 8 setups
Aurkb is upregulated in a subset of fetal/neonatal microglia and in microglia following CPZ-induced demyelination and in MS patient microglia
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Has reproduction
Mapping the Development of Human Spermatogenesis Using Transcriptomics-Based Data: A Scoping Review.
PMID 39000031 · PMC11241379 · International journal of molecular sciences · 2024 · 8 claims · 8 setups
scRNA-seq of human testis reveals major transcriptional modifications occurring around 11 years of age, marking a transition toward the adult cellular state
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Tissue-resident macrophage and dendritic cells drive type I IFN immunity to enteroviruses in the liver.
PMID 41592119 · PMC12858076 · PLoS pathogens · 2026 · 8 claims · 6 setups
Type I IFN signaling (Ifnar1), but not type III IFN signaling (Ifnlr1), is essential for survival and for limiting viral replication in the liver during echovirus infection
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Dual mechanisms of supporting cell regeneration in the neonatal mouse cochlea.
PMID 41867623 · PMC13000480 · iScience · 2026 · 8 claims · 8 setups
GER cells regenerate IPhCs through both mitotic and non-mitotic mechanisms
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Single-cell gene expression and TCR profiling reveal age-related differences in recent thymic emigrants.
PMID 42023153 · PMC13098507 · iScience · 2026 · 8 claims · 5 setups
Neonatal and adult CD8+ RTEs are phenotypically and functionally distinct despite equivalent post-thymic maturation time
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Has reproduction · 67
Leveraging RNA-seq deconvolution to improve complex in vitro model characterization.
PMID 40701251 · PMC12391696 · The Journal of biological chemistry · 2025 · 8 claims · 6 setups
RNA-seq deconvolution can predict cell type proportions from bulk RNA-seq using scRNA-seq references, offering a useful characterization tool for CIVMs where single-cell methods are impractical
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Placental gene signatures associated with high neonatal adiposity: role for immune cell activation.
PMID 41958865 · PMC13061145 · Journal of the Endocrine Society · 2026 · 8 claims · 8 setups
A placental transcriptomic signature is associated with high neonatal adiposity
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Limited protection against early-life lung murine cytomegalovirus infection results from deficiency of cytotoxic CD8 T cells.
PMID 42008567 · PMC13128127 · PLoS pathogens · 2026 · 9 claims · 9 setups
Expansion of endogenous MCMV-specific CD8 T cells is delayed in early life due to a low precursor frequency of peripheral αβ T cells
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Single-cell and spatial transcriptome analysis reveals the potential therapeutic targets for testicular sex cord-stromal cell tumor.
PMID 42057139 · PMC13130799 · Biomarker research · 2026 · 8 claims · 8 setups
Tumor areas of TSCST show significantly low expression of immune cell genes, indicating an immune-cold tumor microenvironment