Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Has reproduction · 76
Single-cell multiomics profiling reveals heterogeneous transcriptional programs and microenvironment in DSRCTs.
PMID 38781959 · PMC11228554 · Cell reports. Medicine · 2024 · 8 claims · 8 setups
DSRCT tumor cells cluster into consistent subpopulations with partially overlapping lineage- and metabolism-related transcriptional programs across patients and samples
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Single-cell transcriptomic analysis reveals intra-tumoral heterogeneity and immunotherapy strategies in high-grade serous ovarian cancer.
PMID 41907410 · PMC13018870 · iScience · 2026 · 8 claims · 8 setups
scRNA-seq of 17 HGSOC tissue samples reveals seven major cell types and extensive intra-tumoral heterogeneity
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Dynamic changes of the immune microenvironment in ovarian cancer following neoadjuvant chemotherapy.
PMID 41872134 · PMC13039919 · Cell death discovery · 2026 · 8 claims · 8 setups
Prostaglandin-mediated immunosuppressive microenvironment formation is a critical contributor to chemotherapy resistance following cisplatin treatment
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MafB is a conserved transcriptional regulator of macrophage development and functional identity across tissues and species.
PMID 41759510 · PMC7618887 · Immunity · 2026 · 8 claims · 8 setups
MafB is required for full differentiation of bone-marrow-derived macrophages (BMDMs) in vitro and for development of most RTMs in vivo
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Patient-derived orthotopic xenograft models recapitulate the peritoneal dissemination of pancreatic cancer and delineate its transcriptional and regulatory programs.
PMID 41673768 · PMC12998334 · Journal of experimental & clinical cancer research : CR · 2026 · 6 claims · 8 setups
Organoids derived from malignant effusions of PDAC patients reproducibly generate peritoneal metastases after orthotopic implantation into the pancreas of immunodeficient mice
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CAF-enriched COL4A6 promotes gastric cancer progression and stromal remodeling despite an inverse association in bulk transcriptomes.
PMID 41735371 · PMC13031391 · Scientific reports · 2026 · 7 claims · 7 setups
COL4A6 carries an inverse association (OR<1) in bulk transcriptome-based risk models despite being markedly upregulated and predominantly localized to the CAF compartment in clinical specimens