Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• Pseudotimecascade Visualizes Gene Expression Cascade in Pseudotime Analysis.

  PMID 41939293 · PMC13047748 · Computational and structural biotechnology journal · 2026 · 8 claims · 6 setups

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  Pseudotimecascade jointly analyzes multiple genes to uncover their relative temporal ordering and stage-specific activation patterns along pseudotime.

  bone genes same scrna-seq single-sample gene

• Telomerase-Associated Genes as Prognostic Markers in High-Grade Serous Ovarian Cancer.

  PMID 42050900 · PMC13137916 · Medical science monitor : international medical journal of experimental and clinical research · 2026 · 8 claims · 8 setups

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  TAGs are linked to HGSOC progression and yield a candidate prognostic model

  hgsoc tcga-ov scrna-seq-derived single-cell bulk cellchat

• Single-Cell and Spatial Transcriptomics Reveal That TXNIP and BIRC3 Contribute to Human Prostate Tumor Progression.

  PMID 41972735 · PMC13072731 · Cells · 2026 · 6 claims · 8 setups

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  TXNIP and BIRC3 are established as spatially restricted tumor-niche genes associated with metabolic stress and inflammatory survival pathways

  prostate tcga-prad integration single-cell spatial pseudotime

• Assessing personalized molecular portraits underlying endothelial-to-mesenchymal transition within pulmonary arterial hypertension.

  PMID 39462326 · PMC11513636 · Molecular medicine (Cambridge, Mass.) · 2024 · 8 claims · 8 setups

  Has reproduction · 81

  scRNA-seq of PAH and control lung tissue identifies nine distinct cell populations with high heterogeneity in composition, function, distribution, and communication

  lung pah scrna-seq-derived endothelial scrna-seq bulk cell-cell

• PD-1 antibody-bound progenitor-exhausted CD8(+) T cells in lymph nodes boost PD-1-blockade anti-tumor immunity in gastrointestinal cancer.

  PMID 41951588 · PMC13237225 · Nature communications · 2026 · 8 claims · 6 setups

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  Progenitor-exhausted CD8+ T cells (CD8-Tpex, TCF7+PDCD1+) are enriched in proximal lymph nodes and proliferate at a high rate after ICI treatment

  esophagogastric cancer surgically tcga scrna-seq scrna reanalysis

• Single-Cell Transcriptome Profiling Reveals Multicellular Ecosystem of Nucleus Pulposus during Degeneration Progression.

  PMID 34825784 · PMC8787427 · Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022 · 8 claims · 6 setups

  Has reproduction · 59

  Human NP contains six transcriptionally distinct NPC subpopulations: HT-CLNPs, effector NPCs, homeostatic NPCs, regulatory NPCs, fibroNPCs, and adhesion NPCs

  npcs scrna-seq-derived ht-clnp-i g-mdscs single-cell rt-qpcr immunohistochemistry

• Longitudinal Profiling of Tumor and Immune Compartments Uncovers Patterns of Dysregulation and Associations with Response in Multiple Myeloma.

  PMID 41364805 · PMC13012255 · Blood cancer discovery · 2026 · 7 claims · 8 setups

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  IFN-γ signaling after autologous stem cell transplant (ASCT) is associated with markers of impaired CD8+ T-cell memory phenotype

  cd138neg cd138pos bone cd8+ single-cell bulk whole-genome

• Clonal CD8(+) T cells populate the leptomeninges and coordinate with immune cells in human degenerative brain diseases.

  PMID 41593242 · PMC12864034 · Nature immunology · 2026 · 8 claims · 6 setups

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  The human leptomeninges harbor substantial numbers of clonally expanded, tissue-resident memory CD8 T cells (ZNF683-high, CXCR6+, PD-1+)

  postmortem leptomeninges scrna-seq-derived leptomeningeal single-cell flow imaging

• Dietary conjugated linoleic acid enhances resistance to Salmonella infection by promoting PPARγ-mediated metabolic reprogramming and effector function in CD8⁺ T cells.

  PMID 41964110 · PMC13078244 · Gut microbes · 2026 · 8 claims · 12 setups

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  Dietary CLA supplementation enhances host resistance to Salmonella Typhimurium infection

  ileal mice serum culture 16s untargeted bulk

• SPRR1B+ keratinocytes prime oral mucosa for rapid wound healing via STAT3 activation.

  PMID 39300285 · PMC11413210 · Communications biology · 2024 · 8 claims · 8 setups

  Has reproduction · 78

  A shared wound healing gene set (P2-WHGs, 146 genes) is constitutively expressed in uninjured oral mucosa but not in uninjured skin

  injured normal p2-whgs oral bulk single-cell gene

• Single-cell transcriptomics identifies regulatory T cell heterogeneity in gestational diabetes mellitus.

  PMID 41933176 · PMC13223204 · Communications medicine · 2026 · 8 claims · 8 setups

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  Treg cluster proportions do not significantly differ between GDM and healthy control patients

  sorted pbmcs treg gdm-patient single-cell mass gene