Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

Publications 1.3k Datasets 392.5k Experiments 10

System / cell line: pathway ✕ Assay: scrna-seq-derived ✕ Clear

Single-cell transcriptomic analysis reveals intra-tumoral heterogeneity and immunotherapy strategies in high-grade serous ovarian cancer.

PMID 41907410 · PMC13018870 · iScience · 2026 · 8 claims · 8 setups

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scRNA-seq of 17 HGSOC tissue samples reveals seven major cell types and extensive intra-tumoral heterogeneity

hgsoc epithelial tcga gse165897 single-cell copy kegg
Assessing personalized molecular portraits underlying endothelial-to-mesenchymal transition within pulmonary arterial hypertension.

PMID 39462326 · PMC11513636 · Molecular medicine (Cambridge, Mass.) · 2024 · 8 claims · 8 setups

Has reproduction · 81

scRNA-seq of PAH and control lung tissue identifies nine distinct cell populations with high heterogeneity in composition, function, distribution, and communication

lung pah scrna-seq-derived endothelial scrna-seq bulk cell-cell
Pseudotimecascade Visualizes Gene Expression Cascade in Pseudotime Analysis.

PMID 41939293 · PMC13047748 · Computational and structural biotechnology journal · 2026 · 8 claims · 6 setups

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Pseudotimecascade jointly analyzes multiple genes to uncover their relative temporal ordering and stage-specific activation patterns along pseudotime.

bone genes same scrna-seq single-sample gene
PD-1 antibody-bound progenitor-exhausted CD8(+) T cells in lymph nodes boost PD-1-blockade anti-tumor immunity in gastrointestinal cancer.

PMID 41951588 · PMC13237225 · Nature communications · 2026 · 8 claims · 6 setups

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Progenitor-exhausted CD8+ T cells (CD8-Tpex, TCF7+PDCD1+) are enriched in proximal lymph nodes and proliferate at a high rate after ICI treatment

esophagogastric cancer surgically tcga scrna-seq scrna reanalysis
Telomerase-Associated Genes as Prognostic Markers in High-Grade Serous Ovarian Cancer.

PMID 42050900 · PMC13137916 · Medical science monitor : international medical journal of experimental and clinical research · 2026 · 8 claims · 8 setups

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TAGs are linked to HGSOC progression and yield a candidate prognostic model

hgsoc tcga-ov scrna-seq-derived single-cell bulk cellchat
Single-cell omics data-driven decoding of tumor clonal evolution through reinforcement learning.

PMID 41998716 · PMC13224513 · Genome medicine · 2026 · 8 claims · 3 setups

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scRevol is an RL-based model that infers tumor clonal evolution from scRNA-seq-derived CNV profiles via a label assignment learning strategy.

simulated lineage ovarian scrna-seq-derived
Single-Cell Transcriptome Profiling Reveals Multicellular Ecosystem of Nucleus Pulposus during Degeneration Progression.

PMID 34825784 · PMC8787427 · Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022 · 8 claims · 6 setups

Has reproduction · 59

Human NP contains six transcriptionally distinct NPC subpopulations: HT-CLNPs, effector NPCs, homeostatic NPCs, regulatory NPCs, fibroNPCs, and adhesion NPCs

npcs scrna-seq-derived ht-clnp-i g-mdscs single-cell rt-qpcr immunohistochemistry
Benchmarking tools for deciphering cellular crosstalk in spatially-resolved transcriptomics.

PMID 41952215 · PMC13174004 · Genome biology · 2026 · 8 claims · 5 setups

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No prior systematic, quantitative benchmark exists for CCI inference methods specifically developed for spatial transcriptomics across multiple platforms

synthetic real simulated simulation spot-purity real-data
Single-cell transcriptomics reveals keratinocyte dynamic processes associated with S100a4 expression in psoriasiform dermatitis.

PMID 41660613 · PMC12876221 · Frontiers in immunology · 2025 · 7 claims · 8 setups

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S100a4 knockout mice show significant pathological improvement in psoriasis-like lesions, including reduced inflammatory cell infiltration and decreased epidermal hyperplasia

c57bl skin dorsal dcmo crispr western imiquimod-induced
Dietary conjugated linoleic acid enhances resistance to Salmonella infection by promoting PPARγ-mediated metabolic reprogramming and effector function in CD8⁺ T cells.

PMID 41964110 · PMC13078244 · Gut microbes · 2026 · 8 claims · 12 setups

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Dietary CLA supplementation enhances host resistance to Salmonella Typhimurium infection

ileal mice serum culture 16s untargeted bulk

Experiments

Single-cell transcriptomic analysis reveals intra-tumoral heterogeneity and immunotherapy strategies in high-grade serous ovarian cancer.

Assessing personalized molecular portraits underlying endothelial-to-mesenchymal transition within pulmonary arterial hypertension.

Pseudotimecascade Visualizes Gene Expression Cascade in Pseudotime Analysis.

PD-1 antibody-bound progenitor-exhausted CD8(+) T cells in lymph nodes boost PD-1-blockade anti-tumor immunity in gastrointestinal cancer.

Telomerase-Associated Genes as Prognostic Markers in High-Grade Serous Ovarian Cancer.

Single-cell omics data-driven decoding of tumor clonal evolution through reinforcement learning.

Single-Cell Transcriptome Profiling Reveals Multicellular Ecosystem of Nucleus Pulposus during Degeneration Progression.

Benchmarking tools for deciphering cellular crosstalk in spatially-resolved transcriptomics.

Single-cell transcriptomics reveals keratinocyte dynamic processes associated with S100a4 expression in psoriasiform dermatitis.

Dietary conjugated linoleic acid enhances resistance to Salmonella infection by promoting PPARγ-mediated metabolic reprogramming and effector function in CD8⁺ T cells.