Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Protein ranking by semi-supervised network propagation.
PMID 16723003 · PMC1810311 · BMC bioinformatics · 2006 · 8 claims · 5 setups
RankProp, a diffusion-based network propagation algorithm on a PSI-BLAST-derived protein similarity network, significantly outperforms local search methods (BLAST/PSI-BLAST) at detecting remote homologs.
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Has reproduction · 87
R2DT is a framework for predicting and visualising RNA secondary structure using templates.
PMID 34108470 · PMC8190129 · Nature communications · 2021 · 8 claims · 6 setups
R2DT is a template-based computational framework/pipeline that predicts and visualises RNA 2D structure in standardised, community-accepted layouts
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Has reproduction · 68
Cell-type annotation with accurate unseen cell-type identification using multiple references.
PMID 37379341 · PMC10335708 · PLoS computational biology · 2023 · 8 claims · 4 setups
mtANN integrates multiple reference datasets and eight gene selection methods via ensemble learning (multiple deep classification models + majority voting) to improve cell-type annotation accuracy
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Animal models of gene-nutrient interactions.
PMID 19037208 · PMC2703433 · Obesity (Silver Spring, Md.) · 2008 · 8 claims · 5 setups
Mice and rats are well-suited models for human food selection because they share food preferences with humans and are supported by extensive genetic tools (sequenced genome, inbred strains, gene targeting, Cre-lox).
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Identification and recovery of minor HIV-1 variants using the heteroduplex tracking assay and biotinylated probes.
PMID 18948297 · PMC2602764 · Nucleic acids research · 2008 · 6 claims · 8 setups
Incorporating a biotin tag into the HTA probe enables purification of labeled heteroduplexes and direct sequencing of the separated query strand, allowing recovery of minor variant sequences
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Has reproduction · 55
Identification and verification of diagnostic biomarkers in recurrent pregnancy loss via machine learning algorithm and WGCNA.
PMID 37691920 · PMC10485775 · Frontiers in immunology · 2023 · 8 claims · 8 setups
352 DEGs (198 up-regulated, 154 down-regulated) were identified between RPL and control endometrial samples
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Systems integration of biodefense omics data for analysis of pathogen-host interactions and identification of potential targets.
PMID 19779614 · PMC2745575 · PloS one · 2009 · 8 claims · 8 setups
A protein-centric data integration approach (Master Protein Directory) enables integration and mining of heterogeneous pathogen-host omics data across multiple research centers