Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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GenBank.
PMID 16381837 · PMC1347519 · Nucleic acids research · 2006 · 8 claims · 8 setups
GenBank is a comprehensive public database of nucleotide sequences with supporting bibliographic and biological annotation, built and distributed by NCBI.
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Environmental Burkholderia cepacia complex isolates in human infections.
PMID 17552100 · PMC2725883 · Emerging infectious diseases · 2007 · 6 claims · 4 setups
More than 20% of clinical Bcc isolates examined are indistinguishable by MLST from environmental isolates, linking the natural environment to emergence of clinical infections
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Has reproduction · 24
MiGPC: a comprehensive catalog of enzybiotics from environmental metagenomes.
PMID 41888223 · PMC13172421 · Scientific reports · 2026 · 8 claims · 8 setups
MiGPC is the first genome-resolved metagenomic gene and protein catalog specifically targeted to enzybiotics
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Dark matter in a deep-sea vent and in human mouth.
PMID 17803764 · PMC2040194 · Environmental microbiology · 2007 · 7 claims · 8 setups
The first genome sequence from the uncultured TM7 phylum was obtained by capturing and sequencing DNA from a single cell using a microfluidic device, yielding a 2.86 Mb assembly with 3245 predicted genes.
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Has reproduction · 78
Fungal metabarcoding data integration framework for the MycoDiversity DataBase (MDDB).
PMID 32463383 · PMC7734503 · Journal of integrative bioinformatics · 2020 · 6 claims · 5 setups
The MycoDiversity DataBase (MDDB) is a curated repository integrating public fungal metabarcoding data of environmental samples to study fungal biodiversity patterns in space and time.
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Charting the map of life.
PMID 11171541 · PMC1242061 · Environmental health perspectives · 2001 · 8 claims · 8 setups
Only 3-5% of the human genome, corresponding to 30,000-100,000 genes, is thought to be biologically functional
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Multilocus sequence typing supports the hypothesis that Ochrobactrum anthropi displays a human-associated subpopulation.
PMID 20021660 · PMC2810298 · BMC microbiology · 2009 · 8 claims · 6 setups
A novel Multi-Locus Sequence Typing (MLST) scheme for O. anthropi was developed for the first time, based on 7 genes (3490 nucleotides) evolving mostly by neutral mutations
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Multilocus sequence typing of Cronobacter sakazakii and Cronobacter malonaticus reveals stable clonal structures with clinical significance which do not correlate with biotypes.
PMID 19852808 · PMC2770063 · BMC microbiology · 2009 · 8 claims · 6 setups
A seven-locus MLST scheme (atpD, fusA, glnS, gltB, gyrB, infB, pps) reliably identifies and discriminates C. sakazakii and C. malonaticus strains
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Genetic diversity among Enterococcus faecalis.
PMID 17611618 · PMC1899230 · PloS one · 2007 · 7 claims · 7 setups
Virulence and antibiotic resistance traits are distributed across many diverse E. faecalis lineages rather than confined to one clade
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Lineage specific recombination rates and microevolution in Listeria monocytogenes.
PMID 18842152 · PMC2576243 · BMC evolutionary biology · 2008 · 8 claims · 6 setups
Recombination is more prevalent in lineage II than in lineage I
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Vibrio cholerae pathogenic clones.
PMID 16318732 · PMC3367346 · Emerging infectious diseases · 2005 · 8 claims · 1 setups
The US Gulf clone, the Australian clone, and 3 prepandemic El Tor strains are related to the seventh pandemic clone.
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Pulmonary biomarkers based on alterations in protein expression after exposure to arsenic.
PMID 17450228 · PMC1852690 · Environmental health perspectives · 2007 · 5 claims · 6 setups
Chronic low-dose As exposure (10/50 ppb) consistently alters expression of specific proteins (RAGE, GST-omega-1, contraspin, ApoA-I, ApoA-IV, peroxiredoxin-6, enolase-1) in mouse lung-lining fluid.
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Integrative functional genomics.
PMID 15239826 · PMC463286 · Genome biology · 2004 · 8 claims · 8 setups
Ultra-conserved noncoding elements exist across human, mouse and rat genomes at very high sequence identity, often far from genes
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Olden times: looking back on a career at the NIEHS.
PMID 15289171 · PMC1247486 · Environmental health perspectives · 2004 · 8 claims · 3 setups
Kenneth Olden served 13 years as director of NIEHS and the National Toxicology Program, the first African American to head an NIH institute
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A big circuit model.
PMID 12940284 · PMC1316925 · Environmental health perspectives · 2003 · 8 claims · 8 setups
In early prostate carcinogenesis, apoptosis signals are primarily suppressed rather than growth rate being increased.
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Has reproduction · 61
Tourmaline: A containerized workflow for rapid and iterable amplicon sequence analysis using QIIME 2 and Snakemake.
PMID 35902092 · PMC9334028 · GigaScience · 2022 · 8 claims · 1 setups
Tourmaline is a Python-based workflow that implements QIIME 2 using the Snakemake workflow management system to automate amplicon sequence analysis.
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Has reproduction · 81
Metatranscriptomics-based investigation of bacterial community dynamics across a dissolved organic matter gradient in southern Lake Michigan.
PMID 41860215 · PMC13101498 · Applied and environmental microbiology · 2026 · 7 claims · 6 setups
DOM composition changes significantly across the nearshore-to-offshore transect, with more terrestrially derived and high-molecular-weight DOM nearshore, despite only minor reductions in DOC and similar inorganic N and P levels.
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Has reproduction · 82
Whole-genome analysis of a multidrug-resistant Klebsiella michiganensis environmental isolate from an orthopedic ward in Mwanza, Tanzania reveals IncF-family plasmid replicon signatures associated with resistance determinants.
PMID 41957580 · PMC13173886 · BMC genomics · 2026 · 6 claims · 8 setups
Genome-based taxonomy (GTDB-Tk and ANI) reclassified the isolate A55848, phenotypically identified as K. oxytoca, as Klebsiella michiganensis
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Genomic approaches to the genetics of alcoholism.
PMID 12875046 · PMC6683845 · Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism · 2002 · 8 claims · 4 setups
Alcoholism is a complex disease that develops from a combination of numerous genetic and environmental factors, unlike single-gene disorders such as cystic fibrosis or Huntington's disease.
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The changing face of genomics.
PMID 15128443 · PMC416465 · Genome biology · 2004 · 8 claims · 8 setups
Genome-wide ChIP-chip mapping of ~200 yeast transcriptional regulators across environmental conditions reveals general principles of promoter architecture and regulatory response types