Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• Wnt3-mediated fibrosis and carcinogenesis of lung squamous cell carcinoma in idiopathic pulmonary fibrosis.

  PMID 42063567 · PMC13127482 · iScience · 2026 · 8 claims · 8 setups

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  LUSC arising within UIP originates from AT2-derived metaplastic basal cells

  fresh-frozen same scrna-seq paired single-cell copy ligand-receptor

• Fast, accurate, and racially unbiased pan-cancer tumor-only variant calling with tabular machine learning.

  PMID 36611079 · PMC9825621 · NPJ precision oncology · 2023 · 8 claims · 8 setups

  Has reproduction

  Tree-based (XGBoost, LightGBM) and deep-learning (TabNet) tabular ML classifiers achieve state-of-the-art somatic vs germline classification in tumor-only WES samples, outperforming PureCN.

  tcga same metastatic tumor-only whole-exome wes copy-number

• Systematic annotation of orphan RNAs reveals blood-accessible molecular barcodes of cancer identity and cancer-emergent oncogenic drivers.

  PMID 41579861 · PMC12923976 · Cell reports. Medicine · 2026 · 8 claims · 8 setups

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  oncRNA binary presence-absence patterns constitute digital molecular barcodes that capture cancer type and subtype identity

  tcga exrna cptac mda-mb-231 small machine atac-seq

• Shared patterns of dysregulated gene expression across squamous cell carcinomas unveil predictors for prognosis and drug sensitivity.

  PMID 41803163 · PMC13096486 · Scientific reports · 2026 · 8 claims · 6 setups

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  SCCs from head and neck (HNSC), esophagus (ESCC), and cervix (CESC) share highly similar dysregulated gene expression patterns (DGEPs), whereas lung (LUSC) and skin (CSCC) SCCs are more molecularly distinct

  tumor combined tcga differential sequencing weighted

• Spatial multi-omics unveils the monoclonal origin, neuroendocrine plasticity, and microenvironment niches in combined small-cell lung cancer.

  PMID 41966692 · PMC13130634 · Cell reports. Medicine · 2026 · 8 claims · 6 setups

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  Different histologic components within cSCLC tumors share a monoclonal origin

  ffpe sections tumor luad multi-region spatial single-nucleus

• Identification and validation of prognostic genes associated with M2 macrophage and heme metabolism in lung adenocarcinoma through bulk and single-cell RNA sequencing analysis.

  PMID 41787185 · PMC13076703 · Discover oncology · 2026 · 8 claims · 8 setups

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  EPB41, ACP5, PPOX, RBM38, and TRIM58 were identified as prognostic genes for LUAD

  tcga-luad gse131907 clinical cibersort gsea spearman