Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Adaptive discriminant function analysis and reranking of MS/MS database search results for improved peptide identification in shotgun proteomics.
PMID 18788775 · PMC3744223 · Journal of proteome research · 2008 · 7 claims · 4 setups
PeptideProphet's fixed LDA coefficients for combining search scores (Xcorr', ΔCn, SpRank) may not be optimal under all search/instrument conditions.
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The impact of peptide abundance and dynamic range on stable-isotope-based quantitative proteomic analyses.
PMID 18798661 · PMC2746028 · Journal of proteome research · 2008 · 8 claims · 7 setups
Over half of confidently identified peptides in complex mixtures have S/N ratios below 10 on both FT-ICR and Orbitrap instruments