Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Protocol for generating and characterizing Matrigel-free prostate cancer patient-derived organoids.
PMID 41955100 · PMC13091043 · STAR protocols · 2026 · 7 claims · 7 setups
A Matrigel-free culture protocol improves both take-rate and proportion of tumor cells within PCa PDO cultures compared to traditional Matrigel-based approaches
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Has reproduction · 65
comBO: A combined human bone and lympho-myeloid bone marrow organoid for preclinical modeling of hematopoietic disorders.
PMID 41734765 · PMC7618947 · Cell stem cell · 2026 · 8 claims · 8 setups
comBO is a single iPSC-derived organoid differentiation that generates osteolineage, vascular, lymphoid, and myeloid compartments together
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Functional human salivary gland organoids for tissue regeneration in chemically defined culture systems.
PMID 41707649 · PMC12923968 · Cell reports. Medicine · 2026 · 8 claims · 8 setups
A chemically defined, Matrigel-free complete medium (CM) generates hSGOs with more cohesive spheroid morphology, organized epithelial layers, and improved apical polarization compared to keratinocyte medium (KM-S) or Matrigel-embedded conditions
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Has reproduction · 72
Neoadjuvant sintilimab plus chemotherapy in EGFR-mutant NSCLC: Phase 2 trial interim results (NEOTIDE/CTONG2104).
PMID 38897205 · PMC11293361 · Cell reports. Medicine · 2024 · 8 claims · 8 setups
Neoadjuvant sintilimab plus carboplatin/nab-paclitaxel is clinically feasible and tolerable in resectable EGFR-mutant NSCLC, with all 18 patients completing treatment and undergoing radical surgery.