Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Rtf1-dependent transcriptional pausing regulates cardiogenesis.
PMID 41537425 · PMC12807453 · eLife · 2026 · 8 claims · 7 setups
Rtf1 activity is essential for differentiation of the myocardial lineage from mesoderm
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Has reproduction · 85
Epigenome screening highlights that JMJD6 confers an epigenetic vulnerability and mediates sunitinib sensitivity in renal cell carcinoma.
PMID 33634984 · PMC7882098 · Clinical and translational medicine · 2021 · 8 claims · 8 setups
JMJD6 is identified as a potent epigenetic vulnerability/fitness gene in RCC by integrating GeCK CRISPR screening data with TCGA-KIRC epigenetic regulator survival analysis
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VHL synthetic lethality screens uncover CBF-β as a negative regulator of STING.
PMID 41820368 · PMC13121600 · Nature communications · 2026 · 8 claims · 8 setups
CBFB (CBF-β) is a synthetic lethal interactor of VHL in ccRCC cell lines
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DOT1L activity limits transcription elongation velocity and favors RNAPII pausing to facilitate mutagenesis by AID.
PMID 41526379 · PMC12905297 · Nature communications · 2026 · 8 claims · 8 setups
DOT1L and super elongation complex (SEC) components are proximal to nuclear AID by BioID
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Has reproduction · 73
FRMD8 inhibits tumor metastasis in BRCA1-associated TNBC by negatively regulating tmTNF-α.
PMID 40619383 · PMC12229025 · Cellular & molecular biology letters · 2025 · 8 claims · 8 setups
Low FRMD8 expression in BRCA1-mutant breast cancer cells significantly enhances metastatic potential to various organs