Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• Sequencing the regulatory genome.

  PMID 18598374 · PMC2481419 · Genome biology · 2008 · 8 claims · 8 setups

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  Nuclear-lamina-associated domains (LADs) define chromatin regions with distinct transcriptional characteristics (fewer, lower-expressed genes, low RNA Pol II occupancy, H3K27me3-enriched borders)

  interphase nine beta-globin drosophila nuclear digital chip

• LINE-1 Locus Transcription Nucleates Oncogenic Chromatin Architecture.

  PMID 41489510 · PMC13040219 · Cancer discovery · 2026 · 8 claims · 8 setups

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  LINE-1 RNAs are primarily chromatin-associated nascent transcripts rather than cytosolic mRNAs

  mcf7 cancer qrt-pcr single-molecule chirp-seq

• EPB41L4A-AS1 long noncoding RNA acts in both cis- and trans-acting transcriptional regulation and controls nucleolar biology.

  PMID 41805684 · PMC12975130 · eLife · 2026 · 8 claims · 8 setups

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  EPB41L4A-AS1 acts in cis to enhance transcription of the proximal EPB41L4A gene

  mcf-7 epb41l4a-as1 rna-seq rt-qpcr single-molecule

• Synthetic super-enhancers enable precision viral immunotherapy.

  PMID 41951744 · PMC13149004 · Nature · 2026 · 8 claims · 8 setups

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  Synthetic super-enhancers (SSEs) assembled from validated 160 bp SOX2/SOX9-bound enhancer fragments achieve strong and highly selective transcriptional activity in glioblastoma stem cells (GSCs)

  gsc7 patient-derived seven id2904 luciferase flow chip-seq