Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Bridging cancer cell-intrinsic driver genes and -extrinsic cell-cell communication with Driver2Comm.
PMID 41701761 · PMC12928580 · PLoS computational biology · 2026 · 8 claims · 5 setups
Driver2Comm is a computational framework that identifies intrinsic-extrinsic (IE) pathways functionally connecting cancer cell driver genes with their associated CCC signatures in the TME using single-cell transcriptomics data.
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The complement system contributes to the immunosuppressive microenvironment of uveal melanoma.
PMID 41803879 · PMC13130498 · Journal of translational medicine · 2026 · 8 claims · 8 setups
Primary UM (pUM) preferentially expresses early complement pathway components over terminal membrane attack complex elements, with early factors showing prognostic significance.
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FOXA1 mutations co-opt nascent transcription factor networks in partnership with androgen receptor to enhance prostate tumorigenicity.
PMID 41621066 · PMC13050545 · Cell reports · 2026 · 8 claims · 8 setups
FOXA1 mutations in a 874-tumor cohort cluster into missense, in-frame indel, and truncation subgroups, with indels concentrated at residues M253/E255