Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Has reproduction · 79
Species-Wide Phylogenomics of the Staphylococcus aureus Agr Operon Revealed Convergent Evolution of Frameshift Mutations.
PMID 35044202 · PMC8768832 · Microbiology spectrum · 2022 · 8 claims · 7 setups
AgrVATE, a novel kmer-based BLASTn and in silico PCR/Snippy pipeline, enables fast, standardized agr group typing and frameshift/null mutation detection from genome assemblies
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The Genetic and Morphological Basis of Local Adaptation to Elevational Extremes in an Alpine Finch.
PMID 41624103 · PMC12853319 · Ecology and evolution · 2026 · 8 claims · 6 setups
Birds in the warmer Piute Pass population were predicted to have longer wings and larger beaks per Allen's rule
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Transcript diversity reflects deleterious RNA processing errors shaped by population size in metazoans.
PMID 41988943 · PMC13001929 · PLoS biology · 2026 · 8 claims · 8 setups
Transcript diversity caused by APA, ATI, and AS decreases with Ne (and correspondingly increases with the Ne proxies life span, body length, and omega) across metazoan species.
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Methods for genome-wide analysis of DNA methylation in intestinal tumors.
PMID 19854208 · PMC2891386 · Mutation research · 2010 · 8 claims · 8 setups
Aberrant DNA methylation, including CpG island hypermethylation of tumor suppressors and genome-wide hypomethylation, is strongly linked to the origin and progression of colorectal cancer.
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Has reproduction · 57
Apoptotic brown adipocytes enhance energy expenditure via extracellular inosine.
PMID 35790189 · PMC9452294 · Nature · 2022 · 8 claims · 8 setups
Apoptotic brown adipocytes release a specific secretome enriched in purine metabolites (including inosine, AMP, hypoxanthine, ATP)
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CHD5, a tumor suppressor gene deleted from 1p36.31 in neuroblastomas.
PMID 18577749 · PMC2483574 · Journal of the National Cancer Institute · 2008 · 7 claims · 8 setups
CHD5 promoter is highly methylated in neuroblastoma cell lines with 1p deletion and absent CHD5 expression (NLF, IMR5)
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Has reproduction · 88
Transcriptome-wide analyses of piRNA binding sites suggest distinct mechanisms regulate piRNA binding and silencing in C. elegans.
PMID 36737102 · PMC10158993 · RNA (New York, N.Y.) · 2023 · 8 claims · 7 setups
C. elegans piRNAs preferentially bind the coding regions (CDS) of target mRNAs in vivo, rather than 3' UTRs.