Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Accurate splice site prediction using support vector machines.
PMID 18269701 · PMC2230508 · BMC bioinformatics · 2007 · 8 claims · 5 setups
Weighted degree (WD) kernel SVMs outperform Markov Chains, GeneSplicer and SpliceMachine for genome-wide splice site recognition
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OPTIC: orthologous and paralogous transcripts in clades.
PMID 17933761 · PMC2238935 · Nucleic acids research · 2008 · 6 claims · 7 setups
OPTIC is a database providing gene predictions and orthology assignments for three clades: amniotes (human, dog, mouse, opossum, platypus, chicken), 12 Drosophila species, and 4 Caenorhabditis nematodes.
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A cell biological perspective on genome research.
PMID 8522596 · PMC2120688 · The Journal of cell biology · 1995 · 7 claims · 7 setups
Genome sequencing represents a sixth stage in the historical progression of structural biology (comparative anatomy through crystallography), and will be similarly valuable once related to function.
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TassDB: a database of alternative tandem splice sites.
PMID 17142241 · PMC1669710 · Nucleic acids research · 2007 · 7 claims · 3 setups
TassDB is a relational database storing GYNGYN donor and NAGNAG acceptor tandem splice sites across eight species
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Shaken not stirred: a global research cocktail served in Hinxton.
PMID 18036269 · PMC2258181 · Genome biology · 2007 · 8 claims · 8 setups
Network-guided reverse genetics using probabilistic functional gene networks (e.g. YeastNet, WormNet) reduces the search space for identifying genes in a given biological process
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Rapid detection and curation of conserved DNA via enhanced-BLAT and EvoPrinterHD analysis.
PMID 18307801 · PMC2268679 · BMC genomics · 2008 · 8 claims · 8 setups
eBLAT detects up to 75% more conserved bases than original BLAT alignments, with the largest gains between evolutionarily distant orthologs
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Advances in the study of SR protein family.
PMID 15626328 · PMC5172405 · Genomics, proteomics & bioinformatics · 2003 · 8 claims · 8 setups
SR proteins promote assembly of the early splicesome via protein-protein interactions in their RS-domain that recruit components of the splicing machinery.