Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

Publications 1.3k Datasets 392.5k Experiments 6

System / cell line: cell-type-specific ✕ Assay: situ ✕ Clear

Endothelial Adgrl2 Expression and Alternative Splicing Controls the Cerebrovasculature.

PMID 41876233 · PMC13108381 · The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026 · 8 claims · 5 setups

Has reproduction · 75

Endothelial cell-specific deletion of Adgrl2 impairs cerebrovascular integrity in mice

wild-type cortex brain single-molecule single-cell immunohistochemistry
Cis-regulatory evolution shapes facial diversity in birds and mammals.

PMID 42090501 · PMC13148318 · Science advances · 2026 · 8 claims · 6 setups

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Mesenchymal populations show markedly greater transcriptomic/regulatory divergence between mouse and chicken than ectodermal populations, pointing to a central role of mesenchyme in shaping facial morphology

embryo chicken embryos single-cell situ cross-species
InSituPREP enables 3D single-cell mapping of interaction-associated gene programs in the breast cancer tumor microenvironment.

PMID 42109251 · PMC13158666 · Nucleic acids research · 2026 · 8 claims · 6 setups

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InSituPREP is a computational framework that quantifies proximity-associated gene programs across multiple analytical layers (binary contacts, graded distance, density, triplets, RNA velocity) in 3D single-cell spatial data

breast adjacent exseq-imaged exseq-derived expansion 16s scrna-seq
Differentiation in the human urothelia is defined by distinct alternative polyadenylation.

PMID 41533515 · PMC12937501 · Cell reports · 2026 · 8 claims · 8 setups

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APA introduces a major layer of transcriptomic diversity during urothelial differentiation, largely independent of changes in mRNA levels

urothelial urothelial-specific ureter hek293t single-cell poly fluorescence
Neuroscience in the era of functional genomics and systems biology.

PMID 19829370 · PMC3645852 · Nature · 2009 · 8 claims · 7 setups

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Omics/discovery-based approaches do not eschew hypotheses but elevate hypothesis testing to high-throughput hypothesis generation and prioritization.

developing hippocampus bac-transgenic fetal situ gene bac-transgenic
SARS-CoV-2 infection during the first trimester leads to profound immune dysregulation at the maternal-fetal interface despite limited virus detection in placental tissues.

PMID 41974725 · PMC13249863 · Nature communications · 2026 · 8 claims · 8 setups

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SARS-CoV-2 rarely infects villous and decidual placental tissues in the first trimester despite maternal infection

villous maternal rt-qpcr fluorescence indirect

Experiments

Endothelial Adgrl2 Expression and Alternative Splicing Controls the Cerebrovasculature.

Cis-regulatory evolution shapes facial diversity in birds and mammals.

InSituPREP enables 3D single-cell mapping of interaction-associated gene programs in the breast cancer tumor microenvironment.

Differentiation in the human urothelia is defined by distinct alternative polyadenylation.

Neuroscience in the era of functional genomics and systems biology.

SARS-CoV-2 infection during the first trimester leads to profound immune dysregulation at the maternal-fetal interface despite limited virus detection in placental tissues.