Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• Cis-regulatory evolution shapes facial diversity in birds and mammals.

  PMID 42090501 · PMC13148318 · Science advances · 2026 · 8 claims · 6 setups

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  Mesenchymal populations show markedly greater transcriptomic/regulatory divergence between mouse and chicken than ectodermal populations, pointing to a central role of mesenchyme in shaping facial morphology

  embryo chicken embryos single-cell situ cross-species

• Genetic parallels in biomineralization of the calcareous sponge Sycon ciliatum and stony corals.

  PMID 40922549 · PMC12419799 · eLife · 2025 · 8 claims · 8 setups

  Has reproduction · 50

  829 genes are overexpressed in regions of increased calcite spicule formation in S. ciliatum, including known sclerocyte-specific biomineralization genes.

  sycon ciliatum cnidarian sponges differential go-term blastp

• De novo H3.3K27M-altered diffuse midline glioma in human brainstem organoids to dissect GD2 CAR T cell function.

  PMID 41492091 · PMC12948678 · Nature cancer · 2026 · 8 claims · 8 setups

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  FGF4 supplementation during organoid patterning specifically induces pontine/rostral hindbrain brainstem identity

  hes brainstem day developing bulk immunofluorescence scrna-seq

• Inferring a spatial code of cell-cell interactions across a whole animal body.

  PMID 36395331 · PMC9714814 · PLoS computational biology · 2022 · 8 claims · 6 setups

  Has reproduction · 90

  cell2cell computes cell-cell interaction (CCI) potential using a novel modified Bray-Curtis score based on complementary coexpression of ligand-receptor pairs between cells

  elegans computational single-cell random genetic

• Tachykinin signaling defines distinct populations of glia in the enteric nervous system.

  PMID 41512855 · PMC12832054 · Neuron · 2026 · 8 claims · 8 setups

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  Mucosal and muscularis glia are transcriptionally distinct populations, with mucosal glia resembling microglia and muscularis glia resembling satellite glia/astrocytes

  ileum gfp+ intestinal intestine bulk scrna-seq bayesprism

• Differential fates of Kazald gene quartet: Ancestral roles in skeletogenesis and regeneration to putative innovations in fish and birds.

  PMID 41782814 · PMC12955574 · iScience · 2026 · 8 claims · 8 setups

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  The regeneration-associated axolotl gene is Kazald2, not Kazald1

  axolotl jawed kazald cyclostome reciprocal tblastn maximum

• Pseudoalteromonas is a symbiont of marine invertebrates that exhibits broad patterns of phylosymbiosis.

  PMID 42007585 · PMC13245728 · The ISME journal · 2026 · 8 claims · 8 setups

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  Pseudoalteromonas is a symbiont with substantial evidence of phylosymbiosis across at least three marine invertebrate phyla (Nematoda, Mollusca, and Cnidaria)

  pseudoalteromonas mollusca individual live pangenomic core-genome average

• Spider: a flexible and unified framework for simulating spatial transcriptomics data.

  PMID 41237053 · PMC12790819 · Bioinformatics (Oxford, England) · 2026 · 8 claims · 6 setups

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  Spider simulates ST data without requiring real ST data as a reference

  simulated hypothalamus dorsolateral spatial clustering cell-cell