Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

Publications 1.3k Datasets 392.5k Experiments 10

System / cell line: saccharomyces ✕ Assay: size ✕ Clear

A cell biological perspective on genome research.

PMID 8522596 · PMC2120688 · The Journal of cell biology · 1995 · 7 claims · 7 setups

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Genome sequencing represents a sixth stage in the historical progression of structural biology (comparative anatomy through crystallography), and will be similarly valuable once related to function.

saccharomyces caenorhabditis selected fruit genomic saturation physical
The nuclear pore complex.

PMID 11574060 · PMC138961 · Genome biology · 2001 · 8 claims · 8 setups

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NPC structure is broadly conserved across eukaryotes but differs substantially in size and architecture between yeast and vertebrates

xenopus saccharomyces yeast caenorhabditis cryo-electron proteomic protein-a
From single cells to whole organisms.

PMID 16420683 · PMC1414103 · Genome biology · 2005 · 8 claims · 8 setups

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The genetic-interaction map in S. cerevisiae is roughly four times as complex as the protein-protein interaction map, and genetic interactions do not overlap with physical interactions but instead predict functional neighborhoods

saccharomyces caenorhabditis mammalian cylindromatosis automated interference rnai
From linear genome sequence to three-dimensional organization of the cell nucleus.

PMID 12620101 · PMC153456 · Genome biology · 2003 · 8 claims · 8 setups

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Chromosome conformation capture (3C) can quantify in vivo physical interaction frequencies between genomic loci by crosslinking, digestion, and intramolecular ligation followed by PCR

saccharomyces mitotic nucleoplasm hela chromosome translocation stretched
Deducing topology of protein-protein interaction networks from experimentally measured sub-networks.

PMID 18598366 · PMC2474618 · BMC bioinformatics · 2008 · 7 claims · 6 setups

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Experimentally measured protein-protein interaction sub-networks are not random samples of their parent networks.

yeast drosophila networks dppi reanalysis computer repeated
Viral and host determinants of RNA virus vector replication and expression.

PMID 15734041 · PMC7115378 · Vaccine · 2005 · 7 claims · 4 setups

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BMV RNA replication occurs in a virus-induced, membrane-bounded compartment rather than in the open cytoplasm.

bmv saccharomyces wild-type immunogold genome-wide northern
Helminth genomics: The implications for human health.

PMID 19855829 · PMC2757907 · PLoS neglected tropical diseases · 2009 · 8 claims · 7 setups

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More than two billion people (one-third of humanity) are infected with helminth parasites, causing major morbidity, mortality, and poverty maintenance

helminth nematode schistosoma strongyloides phylogenetic genome expressed
Genetical genomics: spotlight on QTL hotspots.

PMID 18949031 · PMC2563687 · PLoS genetics · 2008 · 8 claims · 4 setups

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Distant eQTL hotspots are rare and difficult to reliably verify across published genetical genomics studies

adipose saccharomyces genome-wide permutation gene
With the finished human genome in hand, what next?

PMID 12844356 · PMC193627 · Genome biology · 2003 · 8 claims · 8 setups

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Gene Ontology (GO) provides a syntax/query framework for functional classification of genes, expanding beyond E. coli origins into anatomy, pathology, and phenotype data.

domestic saccharomyces systemic schistosoma comparative functional genetic
Microsatellite instability analysis in hereditary non-polyposis colon cancer using the Bethesda consensus panel of microsatellite markers in the absence of proband normal tissue.

PMID 16426447 · PMC1373649 · BMC medical genetics · 2006 · 7 claims · 4 setups

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MSI status can be determined in the absence of proband non-tumor tissue by comparing tumor alleles to alleles carried by the proband's progenitors

proband's peripheral hmsh2 microsatellite direct targeted

Experiments

A cell biological perspective on genome research.

The nuclear pore complex.

From single cells to whole organisms.

From linear genome sequence to three-dimensional organization of the cell nucleus.

Deducing topology of protein-protein interaction networks from experimentally measured sub-networks.

Viral and host determinants of RNA virus vector replication and expression.

Helminth genomics: The implications for human health.

Genetical genomics: spotlight on QTL hotspots.

With the finished human genome in hand, what next?

Microsatellite instability analysis in hereditary non-polyposis colon cancer using the Bethesda consensus panel of microsatellite markers in the absence of proband normal tissue.