Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

Publications 1.3k Datasets 392.5k Experiments 5

System / cell line: regions ✕ Assay: snatac-seq ✕ Clear

Single-cell epigenomics uncovers heterochromatin instability and transcription factor dysfunction during mouse brain aging.

PMID 41824460 · PMC13189690 · Cell reports · 2026 · 8 claims · 6 setups

Full-text index only

Aging causes widespread, concordant changes in chromatin accessibility and gene expression across neuronal and glial cell types in the mouse brain

brain snatac-seq single-nucleus merfish
Genetics and environment distinctively shape the human immune cell epigenome.

PMID 41593234 · PMC12900638 · Nature genetics · 2026 · 8 claims · 6 setups

Full-text index only

Exposure-associated differentially methylated regions (eDMRs) and genotype-associated DMRs (gDMRs) show distinct genomic distributions: eDMRs are enriched at enhancers/regulatory regions, while gDMRs are predominantly found in gene bodies.

pbmcs pbmc edmrs differentially single-nucleus fluorescence-activated motif
Gene regulatory network determinants of rapid recall in human memory CD4(+) T cells.

PMID 41865369 · PMC13207208 · Cell reports · 2026 · 8 claims · 6 setups

Full-text index only

Memory CD4+ T cells show enhanced chromatin accessibility proximal to rapid-recall genes compared to naive cells

blood-derived computational pseudobulk cd4+ single-nuclei maxatac grn
Single-cell spatiotemporal dissection of the human maternal-fetal interface.

PMID 41951740 · PMC13149032 · Nature · 2026 · 8 claims · 8 setups

Full-text index only

Generated a comprehensive single-cell multiomic and spatial atlas of the human maternal-fetal interface from early gestation to term

decidua maternal-fetal pseudobulk trophoblast paired genotype snatac-seq
An integrative single-nucleus multiomic atlas of the human left ventricle identifies gene regulatory network dynamics across cardiac development, aging, and disease.

PMID 41937210 · PMC13067603 · Genome biology · 2026 · 8 claims · 8 setups

Full-text index only

Constructed an integrated multiomic atlas of the human left ventricle combining ~2.3M snRNA-seq nuclei from 299 donors and ~690K snATAC-seq nuclei from 106 donors

left heart cardiac snrna-seq snatac-seq bulk

Experiments

Single-cell epigenomics uncovers heterochromatin instability and transcription factor dysfunction during mouse brain aging.

Genetics and environment distinctively shape the human immune cell epigenome.

Gene regulatory network determinants of rapid recall in human memory CD4(+) T cells.

Single-cell spatiotemporal dissection of the human maternal-fetal interface.

An integrative single-nucleus multiomic atlas of the human left ventricle identifies gene regulatory network dynamics across cardiac development, aging, and disease.