Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• A combined approach exploring gene function based on worm-human orthology.

  PMID 15877817 · PMC1112593 · BMC genomics · 2005 · 8 claims · 6 setups

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  Strict phylogenetic criteria (concordant Neighbor Joining and Maximum Parsimony tree topology) can select single most-likely human orthologs for C. elegans genes despite the large phylogenetic distance between worm and human sequences.

  sapiens elegans hela phylogenetic rnai gfp

• A muscle-centered hierarchical breakdown underlies flight loss during silkworm domestication.

  PMID 41716997 · PMC12915254 · iScience · 2026 · 8 claims · 8 setups

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  Flight loss in B. mori results from a muscle-centered collapse of a three-tiered hierarchical genetic module comprising mitochondrial energy production (COX3/ND1), wing vein patterning (Dally/CtBP), and flight muscle specification (Yki)

  wing wings flight mandarina single-cell spatial velocity

• An ancient genome duplication event drives the development and evolution of spinnerets in spiders.

  PMID 41533794 · PMC12802834 · Science advances · 2026 · 8 claims · 8 setups

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  A single whole-genome duplication (WGD) event occurred in the Arachnopulmonata stem lineage during the Silurian (~438 Ma), supported by macrosynteny, Ks distributions, and WHALE gene-tree reconciliation.

  luthela chelicerate arachnid gene chromosome-scale phylogenomics macrosynteny

• Cis-regulatory evolution shapes facial diversity in birds and mammals.

  PMID 42090501 · PMC13148318 · Science advances · 2026 · 8 claims · 6 setups

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  Mesenchymal populations show markedly greater transcriptomic/regulatory divergence between mouse and chicken than ectodermal populations, pointing to a central role of mesenchyme in shaping facial morphology

  embryo chicken embryos single-cell situ cross-species

• Evolutionary history of the UCP gene family: gene duplication and selection.

  PMID 18980678 · PMC2584656 · BMC evolutionary biology · 2008 · 8 claims · 8 setups

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  The UCP gene family arose through two ancestral gene duplications early in vertebrate evolution, producing the UCP1, UCP2 and UCP3 lineages.

  vertebrate ucp human-mouse ucp1 sequence phylogenetic gene

• Differential fates of Kazald gene quartet: Ancestral roles in skeletogenesis and regeneration to putative innovations in fish and birds.

  PMID 41782814 · PMC12955574 · iScience · 2026 · 8 claims · 8 setups

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  The regeneration-associated axolotl gene is Kazald2, not Kazald1

  axolotl jawed kazald cyclostome reciprocal tblastn maximum