Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Full-text index only
Human Lsg1 defines a family of essential GTPases that correlates with the evolution of compartmentalization.
PMID 16209721 · PMC1262696 · BMC biology · 2005 · 8 claims · 9 setups
hLsg1 is the human orthologue of yeast Lsg1p and defines a family of circularly permuted GTPases named YRG (YlqF Related GTPases)
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Full-text index only
Functional characterisation of the TSC1-TSC2 complex to assess multiple TSC2 variants identified in single families affected by tuberous sclerosis complex.
PMID 18302728 · PMC2291454 · BMC medical genetics · 2008 · 8 claims · 8 setups
Functional assays of TSC1–TSC2 complex activity can distinguish pathogenic TSC2 mutations from rare polymorphisms when multiple variants segregate in one family
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Has reproduction · 94
Fatty acid synthesis suppresses dietary polyunsaturated fatty acid use.
PMID 38167725 · PMC10762034 · Nature communications · 2024 · 7 claims · 8 setups
FASN activity critically determines the use/incorporation of dietary PUFA into complex lipids in mice and humans
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Has reproduction · 64
Sister DNA Entrapment between Juxtaposed Smc Heads and Kleisin of the Cohesin Complex.
PMID 31201089 · PMC6675936 · Molecular cell · 2019 · 8 claims · 8 setups
Smc1 and Smc3 ATPase heads adopt two distinct interaction states in vivo: an ATP-dependent engaged (E) state and a signature-motif juxtaposed (J) state, and these are mutually exclusive.