Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

Publications 1.3k Datasets 392.5k Experiments 6

System / cell line: triple ✕ Assay: specific ✕ Clear

FoxO transcription factors are required for hepatic HDL cholesterol clearance.

PMID 29408809 · PMC5873864 · The Journal of clinical investigation · 2018 · 5 claims · 4 setups

Has reproduction · 49

Mice with liver-specific triple FoxO knockout (L-FoxO1,3,4) have increased HDL cholesterol.

liver-specific l-foxo1 plasma gene hdl
Characterizing gene perturbations in single cells via network divergence analysis.

PMID 41965857 · PMC13249949 · Nature communications · 2026 · 8 claims · 8 setups

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scDNS quantifies gene-specific functional perturbations by measuring Jensen-Shannon divergence between condition-specific gene interaction network configurations

ipsc-derived embryonic panc-1 triple scrna-seq single-nucleus
Endonuclease-independent insertion provides an alternative pathway for L1 retrotransposition in the human genome.

PMID 17517773 · PMC1920257 · Nucleic acids research · 2007 · 8 claims · 5 setups

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An endonuclease-independent pathway (NCLI) for L1 insertion has been active in recent human genome evolution

genome chimpanzee genomic pcr computational triple pcr
Modification of the Creator recombination system for proteomics applications--improved expression by addition of splice sites.

PMID 16519801 · PMC1421398 · BMC biotechnology · 2006 · 8 claims · 8 setups

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The Creator Splice system (5' intron splicing) significantly increases protein expression levels compared to the standard Creator system

hek293t mammalian coli vector immunoblot fluorescence bacterial
T cell-intrinsic VISTA expression promotes resistance to CTLA-4 blockade by restricting CD8+ T cell responses.

PMID 41837284 · PMC12987620 · The Journal of clinical investigation · 2026 · 8 claims · 8 setups

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Loss of T cell-intrinsic VISTA enhances early priming and short-term expansion of CD8+ T cells but this initial advantage fails to confer durable tumor control

tumor vsir cell-specific myeloid-specific flow adoptive peptide
Multi-Omic Profiling of T Cell-Mediated Rejection After Kidney Transplantation Reveals B Cell Receptor Repertoire Expansion and Its Prognostic Relevance.

PMID 41467897 · PMC12752722 · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026 · 8 claims · 8 setups

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The BCR repertoire, particularly the IgG isotype, is significantly expanded in TCMR compared to stable renal function (STA) across independent renal transplant cohorts

kidney healthy lp-1 bcr bulk triple

Experiments

FoxO transcription factors are required for hepatic HDL cholesterol clearance.

Characterizing gene perturbations in single cells via network divergence analysis.

Endonuclease-independent insertion provides an alternative pathway for L1 retrotransposition in the human genome.

Modification of the Creator recombination system for proteomics applications--improved expression by addition of splice sites.

T cell-intrinsic VISTA expression promotes resistance to CTLA-4 blockade by restricting CD8+ T cell responses.

Multi-Omic Profiling of T Cell-Mediated Rejection After Kidney Transplantation Reveals B Cell Receptor Repertoire Expansion and Its Prognostic Relevance.