Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

Publications 1.3k Datasets 392.5k Experiments 4

System / cell line: presence ✕ Assay: spike-in ✕ Clear

Whole genome amplification and de novo assembly of single bacterial cells.

PMID 19724646 · PMC2731171 · PloS one · 2009 · 8 claims · 6 setups

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FACS-based single-cell isolation combined with strict handling procedures virtually eliminates contaminating DNA from single-cell MDA reactions

prochlorococcus single-cell seven sag genome spike-in amplification
Expression and Secretion of Circular RNAs in the Parasitic Nematode, Ascaris suum.

PMID 35711944 · PMC9194832 · Frontiers in genetics · 2022 · 8 claims · 7 setups

Has reproduction · 20

A. suum expresses 1,997 distinct circRNAs identified via next-generation sequencing in adult female body wall and ovary-enriched tissue

suum circrna qrt-pcr drug
Early noninvasive prenatal detection of a fetal CRB1 mutation causing Leber congenital amaurosis.

PMID 18682814 · PMC2493031 · Molecular vision · 2008 · 8 claims · 6 setups

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dHPLC detected the paternally inherited fetal CRB1 mutation (p.Cys896ter) in maternal plasma collected at 12 weeks gestation

maternal serial genomic chorion dhplc automated pcr
Array-based profiling of reference-independent methylation status (aPRIMES) identifies frequent promoter methylation and consecutive downregulation of ZIC2 in pediatric medulloblastoma.

PMID 17344319 · PMC1874664 · Nucleic acids research · 2007 · 7 claims · 7 setups

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aPRIMES is a novel array-based method that detects direct (absolute) methylation status of CGIs via competitive hybridization of McrBC-digested (methylated) versus HpaII/BstUI-digested (unmethylated) DNA from the same genome, avoiding reference-tissue and copy-number biases

pediatric tumor eight desmoplastic aprimes bisulfite quantitative

Experiments

Whole genome amplification and de novo assembly of single bacterial cells.

Expression and Secretion of Circular RNAs in the Parasitic Nematode, Ascaris suum.

Early noninvasive prenatal detection of a fetal CRB1 mutation causing Leber congenital amaurosis.

Array-based profiling of reference-independent methylation status (aPRIMES) identifies frequent promoter methylation and consecutive downregulation of ZIC2 in pediatric medulloblastoma.