Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• Prioritized mass spectrometry increases the depth, sensitivity and data completeness of single-cell proteomics.

  PMID 37012480 · PMC10172113 · Nature methods · 2023 · 8 claims · 5 setups

  Has reproduction · 90

  pSCoPE (prioritized precursor selection via MaxQuant.Live) increases sensitivity, data completeness, and proteome coverage more than twofold over shotgun single-cell proteomics

  bulk hek293 single-cell bone prioritized single-cell spike-in

• MMASS: an optimized array-based method for assessing CpG island methylation.

  PMID 17041235 · PMC1635254 · Nucleic acids research · 2006 · 8 claims · 7 setups

  Full-text index only

  MMASS-v2 (optimized AciI/HinP1I/HpyCH4IV/HpaII enzyme combination with McrBC digestion) offers improved sensitivity and statistical power for microarray-based CpG island methylation detection compared to MMASS-v1, MMASS-sub and the Nouzova method

  hct116 sssi-methylated hcgi12k methylation spike-in cobra

• IDEAL-Q, an automated tool for label-free quantitation analysis using an efficient peptide alignment approach and spectral data validation.

  PMID 19752006 · PMC2808259 · Molecular & cellular proteomics : MCP · 2010 · 6 claims · 5 setups

  Full-text index only

  IDEAL-Q predicts the elution time of peptides unidentified in a given LC-MS/MS run (but identified in others) using a computation-efficient linear regression plus fragmental refining function, avoiding costly whole-dataset pattern recognition

  standard thp-1 replicate lc-ms manual cross-instrument