Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Has reproduction · 62
E3RC: A step-by-step computational protocol for exploring enhancer RNA expression and regulation using conventional RNA-seq data.
PMID 40716058 · PMC12318280 · STAR protocols · 2025 · 6 claims · 3 setups
E3RC is a computational framework for identifying and quantifying eRNAs and characterizing their expression and transcriptional regulation using conventional RNA-seq data.
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miR-203 facilitates timely cell fate transitions via epigenetic modulation during early embryogenesis.
PMID 41811946 · PMC12978216 · Science advances · 2026 · 8 claims · 8 setups
miR-203 is required for a timely totipotency-to-pluripotency transition during early mouse embryogenesis
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SETDB1 enables development beyond cleavage stages by extinguishing the MERVL-driven two-cell totipotency transcriptional program in the mouse embryo.
PMID 41697236 · PMC12908936 · eLife · 2026 · 8 claims · 5 setups
Maternal SETDB1 is required for mouse preimplantation development beyond the eight-cell stage
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Feed-forward loops by NR5A2 ensure robust gene activation during pre-implantation development.
PMID 41355514 · PMC12848575 · Development (Cambridge, England) · 2026 · 8 claims · 8 setups
NR5A2 chromatin binding is dynamic, changing genome-wide from the 2-cell to the morula stage, with peak numbers and target regions (e.g. SINE B1/Alu) shifting over developmental time