Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Monocytes Defined by Platelet Interactions and Oxidative Stress Signaling Underlie HIV-Associated Atherosclerosis.
PMID 41823228 · PMC13055746 · Journal of the American Heart Association · 2026 · 8 claims · 8 setups
Two monocyte clusters (platelet-monocyte complex [PMC] and CD14+ monocytes) contribute independently to vascular immune dysregulation in PLWH
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HIF3A-mediated aberrant activation of TXNIP promotes Alzheimer's disease progression.
PMID 41807716 · PMC13096512 · Scientific reports · 2026 · 8 claims · 8 setups
OS activity is significantly elevated in AD and shows pronounced heterogeneity across brain cell types
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Has reproduction · 80
Synthesis of transcriptomic studies reveals a core response to heat stress in abalone (genus Haliotis).
PMID 40361012 · PMC12070547 · BMC genomics · 2025 · 7 claims · 8 setups
A core set of 74 differentially expressed genes (DEGs) responds to heat stress in at least 7 of 9 independent abalone RNA-seq studies
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Nicotinic acetylcholine receptor subunit variants are associated with blood pressure; findings in the Old Order Amish and replication in the Framingham Heart Study.
PMID 18625075 · PMC2478679 · BMC medical genetics · 2008 · 7 claims · 5 setups
A synonymous coding SNP (rs2099489) in CHRNG is associated with higher systolic blood pressure in both the Old Order Amish (AFDS) and the Framingham Heart Study
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Alcohol consumption and breast tumor mitochondrial DNA mutations.
PMID 19847642 · PMC4403627 · Breast cancer research and treatment · 2010 · 8 claims · 6 setups
Somatic mtDNA mutations are a frequent occurrence in breast tumors
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Paneth cell SIRT1 deficiency increases intestinal stress resistance by modulating the gut microbiota.
PMID 41826553 · PMC13076647 · EMBO reports · 2026 · 8 claims · 8 setups
Generated a novel Paneth-cell-specific SIRT1 knockout mouse model (SIRT1 PKO, Sirt1 f/f;Defa6-Cre+)
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Metabolic adaptations rewire CD4(+) T cells in a subset-specific manner in human critical illness with and without sepsis.
PMID 41540263 · PMC12864044 · Nature immunology · 2026 · 8 claims · 7 setups
CD4+ T cells in critical illness show subset-specific metabolic plasticity, with regulatory T (Treg) cells preferentially acquiring glycolytic capacity
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Negative emotionality: monoamine oxidase B gene variants modulate personality traits in healthy humans.
PMID 19657584 · PMC3653168 · Journal of neural transmission (Vienna, Austria : 1996) · 2009 · 7 claims · 7 setups
MAOB SNPs rs10521432 and rs6651806 are significantly associated with Negative Emotionality in healthy volunteers
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Ex Vivo Immuno-Oncology Platform Reveals Spatial T-cell Infiltration Patterns Linked to ATR Inhibition Responses in High-Grade Serous Ovarian Cancer.
PMID 41563843 · PMC7618831 · Cancer immunology research · 2026 · 8 claims · 8 setups
iPDCs cultured on human omentum gel (OmGel) recapitulate tumor genomic and histologic characteristics while retaining intratumoral immune cells
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Has reproduction · 71
Transcriptomic Study on the Lungs of Broilers with Ascites Syndrome.
PMID 36611783 · PMC9817706 · Animals : an open access journal from MDPI · 2023 · 8 claims · 6 setups
1442 genes were differentially expressed in AS broiler lung vs normal lung (614 up-regulated, 828 down-regulated)
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Has reproduction · 83
Mural cell-derived chemokines provide a protective niche to safeguard vascular macrophages and limit chronic inflammation.
PMID 37652021 · PMC10588993 · Immunity · 2023 · 7 claims · 8 setups
Vascular macrophages form a spatiotemporal niche in direct contact with mural cells across microvascular and macrovascular beds
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Phenotypic screening, transcriptional profiling, and comparative genomic analysis of an invasive and non-invasive strain of Candida albicans.
PMID 18950481 · PMC2579918 · BMC microbiology · 2008 · 8 claims · 8 setups
Strain SC5314 is invasive and virulent whereas strain ATCC10231 is non-invasive and strongly attenuated in virulence
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Protective effect of KCNH2 single nucleotide polymorphism K897T in LQTS families and identification of novel KCNQ1 and KCNH2 mutations.
PMID 18808722 · PMC2570672 · BMC medical genetics · 2008 · 8 claims · 7 setups
LQTS-associated mutations were identified in 8 of 112 families studied
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Has reproduction · 87
Covalent binding of thioredoxin to TXNIP is required for diet-induced insulin resistance in the liver.
PMID 40345590 · PMC12180993 · The Journal of biological chemistry · 2025 · 8 claims · 9 setups
TXNIP Cysteine 247 is required for high-fat diet-induced hepatic and whole-body insulin resistance in mice
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KEGG spider: interpretation of genomics data in the context of the global gene metabolic network.
PMID 19094223 · PMC2646283 · Genome biology · 2008 · 8 claims · 8 setups
KEGG spider, using a global 'pathway-free' metabolic network framework, provides deeper insight into metabolism variations than existing enrichment-based methods.