Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• Comparison between short-term stress and long-term adaptive responses reveal common paths to molecular adaptation.

  PMID 35243257 · PMC8873613 · iScience · 2022 · 8 claims · 7 setups

  Has reproduction · 59

  Short-term stress and long-term adaptations share common metabolic pathways

  great embryonic gef mapk1 bulk gene transcription

• Stress testing reveals selective vulnerabilities in protein homeostasis.

  PMID 41575849 · PMC13040462 · Cell reports · 2026 · 8 claims · 8 setups

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  Tn-seq fitness profiling across strains lacking major chaperones/proteases under proteotoxic stress reveals stress- and strain-specific fitness determinants otherwise masked by redundancy

  caulobacter transposon growth sequencing

• Systematic background selection with BasCoD enhances contrastive dimension reduction in single cell genomics.

  PMID 41844632 · PMC13144610 · Nature communications · 2026 · 8 claims · 7 setups

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  BasCoD is a statistical testing framework using spectral subspace inclusion theory to evaluate whether a candidate background dataset is suitable for contrastive dimension reduction of a target dataset

  ts65dn ipscs k562 intestinal contrastive population-scale perturb-seq

• Signatures of Innovation and Selection in the Extremotolerant Yeast Kluyveromyces marxianus.

  PMID 41874284 · PMC13011806 · Genome biology and evolution · 2026 · 8 claims · 9 setups

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  K. marxianus shows a unique stress-resistance syndrome (heat, ethanol, caffeine, propidium iodide, MMS) relative to other Kluyveromyces species

  kluyveromyces marxianus one-to-one liquid heat-shock stress

• Negative emotionality: monoamine oxidase B gene variants modulate personality traits in healthy humans.

  PMID 19657584 · PMC3653168 · Journal of neural transmission (Vienna, Austria : 1996) · 2009 · 7 claims · 7 setups

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  MAOB SNPs rs10521432 and rs6651806 are significantly associated with Negative Emotionality in healthy volunteers

  healthy genotype maoa snp multidimensional profile