Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• Haplotype-resolved genome assemblies of BJ and IMR-90 human fibroblast cell lines reveal extensive structural variation and enable reanalysis of historical sequencing data.

  PMID 42049241 · PMC13124242 · Nucleic acids research · 2026 · 8 claims · 8 setups

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  Chromosome-level, phased diploid genome assemblies were generated for BJ and IMR-90 fibroblast cell lines spanning 5.9 and 6.0 Gbp with diploid QV exceeding 60

  imr-90 pacbio oxford hi-c

• Personalized genomic medicine with a patchwork, partially owned genome.

  PMID 18449389 · PMC2347364 · The Yale journal of biology and medicine · 2007 · 8 claims · 6 setups

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  Structural variants (CNVs) cover as much as 20 percent of the human genome length and are present in phenotypically normal individuals without apparent negative consequences.

  phenotypically single genome chimpanzee molecular diploid encode

• The diploid genome sequence of an individual human.

  PMID 17803354 · PMC1964779 · PLoS biology · 2007 · 7 claims · 6 setups

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  Generated an independently assembled diploid human genome sequence (HuRef) from both chromosome sets of a single individual using whole-genome shotgun Sanger sequencing

  donor huref whole-genome assembly-to-assembly snp

• The 1000 Chinese Pangenome empowers medical and population genetics.

  PMID 41922767 · PMC13233627 · Nature · 2026 · 8 claims · 8 setups

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  1,116 diploid genome assemblies (55 de novo, 1,061 pangenome-informed) were generated as part of the 1KCP project

  genomic diploid benchmark illumina pacbio hi-c

• The HuRef Browser: a web resource for individual human genomics.

  PMID 19036787 · PMC2686481 · Nucleic acids research · 2009 · 7 claims · 6 setups

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  The HuRef Browser is a unified web application integrating assembly, annotation, and assembly-to-assembly comparison (ATAC) views for the diploid HuRef individual human genome.

  individual huref whole-genome assembly-to-assembly variant

• Intraspecies sequence-graph analysis of the Phytophthora theobromicola genome reveals a dynamic structure and variable effector repertoires.

  PMID 41140028 · PMC12774592 · G3 (Bethesda, Md.) · 2026 · 8 claims · 8 setups

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  Generated long-read genome assemblies for two P. theobromicola isolates (MB01960, P0449) and short-read assemblies for five additional isolates

  theobromicola additional cacao genomes long-read short-read rna-seq

• Dissecting the homeodomain MAT locus and engineering novel tripolar and bipolar mating systems in Cryptococcus amylolentus.

  PMID 41841731 · PMC13059729 · mBio · 2026 · 8 claims · 8 setups

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  A CRISPR-Cas9 gene editing system was developed and optimized for C. amylolentus

  amylolentus diploid sxi1 mating scanning flow

• Genome-Wide Survey and Development of the First Microsatellite Markers Database (AnCorDB) in Anemone coronaria L.

  PMID 35328546 · PMC8949970 · International journal of molecular sciences · 2022 · 8 claims · 8 setups

  Has reproduction · 55

  Generated the first draft genome assembly of A. coronaria by Illumina sequencing a haploid androgenetic plant

  haploid mistral assembled masked whole-genome k-mer genome-wide

• Segmental copy number amplifications are more stable than aneuploidies in the absence of selection.

  PMID 41968576 · PMC13107562 · Molecular biology and evolution · 2026 · 8 claims · 6 setups

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  Segmental amplifications are stable in the absence of selection, whereas aneuploidies are rapidly lost and revert to single-copy genotype

  cerevisiae computational long-term pairwise content