Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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BioAfrica's HIV-1 proteomics resource: combining protein data with bioinformatics tools.
PMID 15757512 · PMC555852 · Retrovirology · 2005 · 8 claims · 3 setups
BioAfrica's HIV-1 Proteomics Resource integrates protein structure, gene expression, post-translational modification, functional activity and protein-macromolecule interaction data with bioinformatics tools in a single website.
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High genetic variability of HIV-1 in female sex workers from Argentina.
PMID 17697319 · PMC1971708 · Retrovirology · 2007 · 7 claims · 6 setups
HIV-1 genetic diversity among Argentine FSWs is extensive, with BF recombinants predominating over subtypes B and C
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Net positive charge of HIV-1 CRF01_AE V3 sequence regulates viral sensitivity to humoral immunity.
PMID 18787705 · PMC2527523 · PloS one · 2008 · 8 claims · 5 setups
Reduction in V3's net positive charge makes V3 less variable due to limited positive selection
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Evolutionary modeling of rate shifts reveals specificity determinants in HIV-1 subtypes.
PMID 18989394 · PMC2566816 · PLoS computational biology · 2008 · 7 claims · 4 setups
A novel Bayesian method, RASER, can detect site-specific evolutionary rate shifts and the lineages in which they occurred without pre-specifying candidate lineages.
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New and old complex recombinant HIV-1 strains among patients with primary infection in 1996-2006 in France: the French ANRS CO06 primo cohort study.
PMID 18673538 · PMC2553414 · Retrovirology · 2008 · 7 claims · 5 setups
04FR-KZS clusters with two previously described DRC viruses and represents CRF27_cpx, a complex recombinant involving A/E/G/H/J/K/U subtypes.
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SNAP: predict effect of non-synonymous polymorphisms on function.
PMID 17526529 · PMC1920242 · Nucleic acids research · 2007 · 7 claims · 8 setups
SNAP, a neural network-based method using sequence-derived information, predicts whether a non-synonymous SNP is neutral or non-neutral for protein function
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Systems biology and the host response to viral infection.
PMID 18066032 · PMC7097743 · Nature biotechnology · 2007 · 8 claims · 8 setups
Systems biology integration of 'omics data (transcriptomics, proteomics, genomics) with computational modeling is needed to fully understand virus-host interactions and identify novel antiviral targets