Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• A gene signature related to programmed cell death to predict immunotherapy response and prognosis in colon adenocarcinoma.

  PMID 39950044 · PMC11823652 · PeerJ · 2025 · 8 claims · 8 setups

  Has reproduction · 73

  COAD patients can be divided into two molecular subtypes (S1, S2) based on 21 prognostic PCD-related genes, with S1 showing worse prognosis and immunosuppressive microenvironment, S2 showing better prognosis and stronger anti-tumor immunity

  coad consensus cibersort mcp-counter

• Distinct molecular and tumor microenvironment characteristics of mucinous adenocarcinoma in colorectal cancer.

  PMID 42100746 · PMC13145884 · iScience · 2026 · 8 claims · 8 setups

  Full-text index only

  MAC is associated with significantly worse overall survival than CAC, but only within the MSS subtype

  tcga-crc surgically crc epithelial whole-exome copy consensus

• Evaluating deconvolution methods using real bulk RNA-expression data for robust prognostic insights across cancer types.

  PMID 41566530 · PMC12906006 · Genome biology · 2026 · 7 claims · 6 setups

  Full-text index only

  Pseudobulk and real bulk RNA-seq deconvolution performance differ significantly, and method ranking consistency is lower between pseudobulk and real bulk than within either data type alone

  breast real colon tcga paired pseudobulk bulk

• UBE2M as a bridge spanning neddylation and cell cycle regulation in colorectal adenocarcinoma.

  PMID 41680469 · PMC12993059 · Experimental & molecular medicine · 2026 · 8 claims · 8 setups

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  Neddylation is associated with G2M phase progression in CRC

  crc paired hek293t cell-free single-cell bulk immunohistochemistry

• Machine learning-driven transcriptomic and single-cell profiling of programed cell death patterns in colon cancer.

  PMID 41854308 · PMC13009810 · Science progress · 2026 · 8 claims · 8 setups

  Full-text index only

  Disulfidptosis and anoikis are consistently identified as the most robust prognostic PCD patterns in colon cancer across six independent machine learning algorithms

  colon coad ssgsea-based machine differential

• Multi-Transcriptomic Analysis Reveals That EREG-Driven TME Crosstalk Defines Anti-EGFR Response in Colorectal Cancer.

  PMID 42043480 · PMC13115984 · Cancer medicine · 2026 · 8 claims · 8 setups

  Full-text index only

  EGFRI eligibility (defined by left-sidedness, RAS/BRAF wild-type, MSS) stratifies cancer cell transcriptomic characteristics more strongly than sidedness alone.

  crc epcam+ aggregated cancer scrna-seq copy pseudobulk